Clinical and Demographic Features of Twenty-Nine Patients with Psoriatic Arthritis “Sine Psoriasis”

Abstract

Psoriatic Arthritis (PsA) is a chronic progressive inflammatory disease that affects 10-30% of patients with psoriasis (PsO). The term "PsA sine psoriasis" is used to describe "patients diagnosed with PsA without skin manifestations". In this study, it was aimed to define the demographic and clinical features of “PsA” “sine psoriasis” according to CASPAR criteria.

Patients and Methods

Twenty-nine patients diagnosed with PsA sine psoriasis according to CASPAR criteria between 2016-2022 were included in the study. Patients with rheumatic diseases and any skin involvement were excluded from the study.

Results

All twenty-nine patients included in the study were diagnosed with PsA according to the CASPAR criteria. 16 of the patients were female. The mean (±SD) age of the patients was 45±11 years. The mean (±SD)  PsA duration of the patients was 6.2±3.0 years. A history of psoriasis in the first-degree relatives of patients with PsA was 54.1%; A history of psoriasis in second-degree relatives was found in 45.9%. 39.4% patients had polyarticular, 35.7% had oligoarticular, 24.9% had axial involvement. DIP involvement was present in 19 (65.5%) of all patients. Nail findings were present in 88.9% of the patients. Besides, enthesitis was detected in 17 (58.6%) and dactylitis was in 18 (62%) of patients.

Conclusion

Patients with clinical symptoms and findings suggestive of PsA and a family history of psoriasis can be classified as PsA sine psoriasis. Patients with dactylitis and DIP arthritis, familial psoriasis may represent a subgroup of PsA.