Comparison of TC-99M sestamibi with I-131 whole Body Scans in Differentiated Thyroid Carcinoma Patients

Hanife Aslı Ayan, Asım Akın, Gökhan Koca, K. Metin Kır

  • Yıl : 2004
  • Cilt : 20
  • Sayı : 4
  •  Sayfa : 128-134
This study evaluated the potential of Tc-99m sestamibi whole body scan as an alternative to whole body I-131 scan for well differentiated thyroid cancer patients prior to I-131 ablation and post ablation states. We evaluated 115 patients with differentiated thyroid cancer who had total or near total thyroidectomy. All patients had undergone Tc-99m sestamibi whole body scanning high resolution neck ultrasonography prior to conventional I-131 whole body scanning, thyroglobulin and antithyroglobulin values measured. Also all patients had neck and chest CT without contrast agent. The results showed that Tc-99m sestamibi whole body images are highly sensitive and specific in differentiated thyroid carcinoma patients without thyroid supression (T4-off), compared to conventional I-31 whole body scans (kappa=0.68 p<0.001). Neck USG with Tc-99m sestamibi is comparable with conventional iodine based whole body studies also compared to high döşe post-ablation 6th day I-131 whole body scans. Neck USG increases sensitivity and decreases specificity of Tc-99m sestamibi scans. Clinical investigations had to be made to evaluate the efficiency of Tc-99m sestamibi in patients receiving thyroid supression.
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Açıklama : Yazarların hiçbiri, bu makalede bahsedilen herhangi bir ürün, aygıt veya ilaç ile ilgili maddi çıkar ilişkisine sahip değildir. Araştırma, herhangi bir dış organizasyon tarafından desteklenmedi.Yazarlar çalışmanın birincil verilerine tam erişim izni vermek ve derginin talep ettiği takdirde verileri incelemesine izin vermeyi kabul etmektedirler.
Comparison of TC-99M sestamibi with I-131 whole Body Scans in Differentiated Thyroid Carcinoma Patients
, Vol. 20 (4)
Geliş Tarihi : 24.11.2004, Kabul Tarihi : 24.11.2004, Yayın Tarihi : 01.10.2020
Selçuk Tıp Dergisi
ISSN:1017-6616;
E-ISSN:2149-8059;