Diffusion Mri Findings Of Basal Ganglia And Thalamus In Hypertension And Diabetes Mellitus

It is known that development of lacunar infarcts were seen due to involvement of lentikulositrial and talamoperforan arteries in hypertension and diabetes mellitus. In this study, we aimed to compare ADC (apparent diffusion coefficient) values of basal ganglia and talamus free of lacunar infarct in patients with diabetes mellitus and hypertension and individuals who have not any systemic diseases. Cranial MR imagings of 52 patients with hypertension, 8 patients with diabetes mellitus and 116 patients with a symptom like headache or vertigo but without any systemic disease were analyzed for ADC values at the levels of caudat nucleus, thalamus and lentiform nucleus. Results were evaluated for statistically. Statistically important difference was found between individuals without systemic disease and patients with diabetes mellitus for ADC values of left lentiform nucleus (p< 0.05). Statistically important difference was determined between hypertensive patients and healthy individuals for ADC values of both thalamus and lentiform nucleus (p<0.05). Even there is no distinct lacunar infarct, differences in ADC values of basal ganglia and thalamus in patients with diabetes mellitus and hypertension may represent microscopic chronic ischemia or developing lacunar infarct.