10-YEAR ENDOMETRIUM CANCER MANAGEMENT IN OUR CLINIC

ABSTRACT

Objective: Endometrial cancer is the most common malignancy of the female genital tract and the fourth leading cancer among women. Our aim is to share the surgical treatment and results of endometrial cancer cases in our gynecological oncology clinic.

Material and Methods: In this study, the records of 164 endometrial cancer patients operated by the same surgical team between 2009-2019 were reviewed retrospectively. The clinical, surgical and histopathological features of the patients are presented here. Four patients who had sarcoma as a result of pathology, 7 patients who underwent complementary surgery and 1 patient with a second primary tumor were not included in the study.

Results: The mean age of the patients included in our study was 61.3 and the mean body mass index was 25.8. According to the postoperative pathology results; mean tumor size was 3.4 cm and mean number of collected lymph nodes was 28.8. Lymph node metastasis was observed in 19 patients and all of the metastases were in pelvic lymph nodes. Endometrioid type adenocarcinoma was seen in 81% of the patients. Myometrial invasion > 50% in 81 patients (49.4%). Twenty patients (12.2%) had cervical involvement, 11 patients (6.7%) had adnexal involvement and 28 patients (17.1%) had lymphovascular area invasion. 76 patients (46.3%) were grade 1, 61 patients (37.2%) were grade 2, 19 patients (11.6%) were grade 3. When the patients were staging according to the FIGO system in 2009, 70 (42.7%) stage 1A, 58 (35.4%) stage 1B, 12 (7.3%) stage 2, 3 (1.8%) stage 3A 17 patients (10.4%) were stage 3C1 and 4 patients (2.4%) were stage 4.

Conclusion: Endometrial cancer is the most common gynecological cancer, and it is usually diagnosed at an early stage as a result of early signs. Tumor size, depth of myometrial invasion and histopathologic grade are used to evaluate the risk of the disease, but studies with a higher number of high stage patients will be more useful in determining the risk.