A Model of Cerebral Ischemia Using a Homologous Blood Embolism in Rabbits

Osman Acar, SABİHA SERPİL KALKAN, ERDAL KALKAN, Hamiyet Pekel, Ahmet Candan Durak

  • Year : 1989
  • Vol : 5
  • Issue : 1
  •  Page : 37-50
In this study, a modified embolic cerebral ischemia model using homologous blood clot as embolizing agent in rabbits is presented. In the study in which 16 rabbits were used, homologous blood clot was injected into the right carotid cournirdsarteri. In all rabbits, the fundus of the eye was examined intermittently before and after embolization, and carotid angiography was performed in four of them to monitor the progression of the embolism. The brains of rabbits killed by giving intracardiac formaldehyde 24 hours after embolization were removed and the localizations and volumes of the infarct sites were determined in serial sections.
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Description : None of the authors, any product mentioned in this article, does not have a material interest in the device or drug. Research, not supported by any external organization. grant full access to the primary data and, if requested by the magazine they agree to allow the examination of data.
A Model of Cerebral Ischemia Using a Homologous Blood Embolism in Rabbits
, Vol. 5 (1)
Received : 23.11.1989, Accepted : 23.11.1989, Published Online : 23.11.2020
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ISSN:1017-6616;
E-ISSN:2149-8059;