A Model of Cerebral Ischemia Using a Homologous Blood Embolism in Rabbits

Osman Acar, SABİHA SERPİL KALKAN, ERDAL KALKAN, Hamiyet Pekel, Ahmet Candan Durak

  • Osman Acar: Selçuk Üniversitesi Meram Tıp Fakültesi
  • SABİHA SERPİL KALKAN: SELÇUK ÜNİVERSİTESİ
  • ERDAL KALKAN: SELÇUK ÜNİVERSİTESİ
  • Hamiyet Pekel: Selçuk Üniversitesi Meram Tıp Fakültesi
  • Ahmet Candan Durak: Erciyes Üniversitesi Tıp Fakültesi
  • Year : 1989
  • Vol : 5
  • Issue : 1
  •  Page : 37-50
In this study, a modified embolic cerebral ischemia model using homologous blood clot as embolizing agent in rabbits is presented. In the study in which 16 rabbits were used, homologous blood clot was injected into the right carotid cournirdsarteri. In all rabbits, the fundus of the eye was examined intermittently before and after embolization, and carotid angiography was performed in four of them to monitor the progression of the embolism. The brains of rabbits killed by giving intracardiac formaldehyde 24 hours after embolization were removed and the localizations and volumes of the infarct sites were determined in serial sections.

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Conflict of interest : Yok
This article is published under the CC BY-NC 4.0 license.
Selcuk Medical Journal
1989, Vol. 5 (1)
ISSN: 1017-6616
E-ISSN: 2149-8059
Received : , Accepted : , Published Online :