Association Between Sleep Problems and Quality of life in Idiopathic Parkinson’s Disease: Findings from Multiple Centers in Turkey

Objective: This study investigated the prevalence of sleep disturbances and their association with sleep quality and overall well-being in Turkish patients diagnosed with idiopathic Parkinson’s disease. Materials and Methods: This collaborative cross-sectional study included a total of 451 patients with idiopathic Parkinson’s disease across Türkiye. Demographic characteristics and relevant clinical information were systematically recorded. Sleep quality, health-related quality of life, and depressive symptoms were assessed using the Parkinson’s Disease Sleep Scale, Parkinson’s Disease Questionnaire 39, and Beck Depression Inventory, respectively. Results: The mean age of the participants was 69.13 ± 11.27 years. According to the modified Hoehn and Yahr staging, most patients were categorized as stage 1 (24.8%), while very few had stage 5 disease (1.3%). Depressive symptoms were moderate in 30.6%, minimal in 29.9%, mild in 24.6%, and severe in 14.9% of the participants. Older age was associated with a significant decline in both sleep onset and sleep benefit scores. Longer disease duration and higher disease stage were associated with decreases in all domains of sleep quality. Depression scores were directly correlated with quality-of-life scores (p<0.001), indicating a strong association between increased depressive symptoms and poorer quality of life in all domains. Conclusion: Sleep disturbances are prevalent in individuals with Parkinson’s disease and have a marked adverse impact on their emotional state and daily functioning. Addressing these sleep problems may contribute to better emotional well-being and enhanced quality of life in this population.