Effect of Verapamil on Contraction due to Bariaın in Isalated Rat Aorta

Ekrem Çiçek, ERGİN ŞİNGİRİK, Necdet Doğan, Erdoğan Özkal

  • Ekrem Çiçek: Süleyman Demirel Üniversitesi Tıp Fakültesi
  • ERGİN ŞİNGİRİK: ÇUKUROVE ÜNİV
  • Necdet Doğan: Selçuk Üniversitesi Meram Tıp Fakültesi
  • Erdoğan Özkal: Selçuk Üniversitesi Tıp Fakültesi
  • Year : 1989
  • Vol : 5
  • Issue : 2
  •  Page : 9-12
With an isolated rat aorta, Ba2+ used al a cumulative concentraiion created a dose-clependent contraction. This contraction is inhibited by verapamil. in a medium containing no Ca2+, it caused Utile but significant contraction compared ta the responses of control group. This contraction isn't inhibited by verapamil. Findings suggest that Ba2+ caused contraction by increasing the extracellular Ca2 + entry and alsa contributed to the intracellular processes.

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Conflict of interest : Yok
This article is published under the CC BY-NC 4.0 license.
Selcuk Medical Journal
1989, Vol. 5 (2)
ISSN: 1017-6616
E-ISSN: 2149-8059
Received : , Accepted : , Published Online :