Evaluation of Antihypertensive Efficacy of Single Dose Enalapril with 24 Hour A nıbulatory Blood Pressure Monitoring

Oktay Ergene, Ömer Kozan, Ali Bayram, İsmet Dindar, Serdar Aksöyek, Oral Pektaş

  • Oktay Ergene: Koşuyolu Kalp ve Araştırma Hastanesi
  • Ömer Kozan: Koşuyolu Kalp ve Araştırma Hastanesi
  • Ali Bayram: Karadeniz Teknik Üniversitesi Tıp Fakültesi
  • İsmet Dindar: Koşuyolu Kalp ve Araştırma Hastanesi
  • Serdar Aksöyek: Hacettepe Üniversitesi Tıp Fakültesi
  • Oral Pektaş: Koşuyolu Kalp ve Araştırma Hastanesi
  • Year : 1993
  • Vol : 9
  • Issue : 1
  •  Page : 78-82
Thirty-nine patients with mild to moderate hypertension were studied at Koşuyolu Heart and Research Hospital between March 1992 and September 1992. The patients were giyen increasing doses of enalapril to a maximum dose of 20 mglday and if necessary diuretic. Ambulatoly pressures were monitored at base line and at the end of 4 weeks of treatment in the case of responders. Total responder rate was 74%. Pre and post treatment mean arterial pressures were 148±9/95±4 and 136±5/87±4 mmHg, respectively (p<0.001). Between 2300-0700 hours these values were 138±5192±3 and 130±5/84±4 mmlig, respectively (p<0.01). Treatment was stopped in one case because of adverse drug effect. In summary enalapril is well tolerated and once daily administiration appeared to be ellective in mild to moderate hypertension

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Conflict of interest : Yok
This article is published under the CC BY-NC 4.0 license.
Selcuk Medical Journal
1993, Vol. 9 (1)
ISSN: 1017-6616
E-ISSN: 2149-8059
Received : , Accepted : , Published Online :