The Clinical Significance Of Calcium And Serum Phosphate In Patients With Acute Appendicitis

The aim of this study was to evaluate the primary changes in laboratory test results and assess how this alters the risk of rupture for patients with acute appendicitis. In addition, we sought to analyze the evolution of this process in order to provide a possible early diagnosis. This study was comprised of 110 patients (58 females and 52 males) who underwent emergency appendectomies at the general surgery clinic. Serum calcium (Ca), phosphate (P) and C-reactive protein (CRP) levels of the patients were measured along with the white blood cell (WBC) count. The prospektif study participants were placed into the perforated (n=30) or non-perforated (n=80) group. The preoperative P value in the non-perforated group was lower (2.66 ± 0.58 mg/dl) than the perforated group (2.95 ± 0.46 mg/dl), and this was statistically significant (p=0.024). While there were no significant changes in the Ca and P levels in the non-perforated group in the pre- and postoperative periods, there were significant decreases in the WBC count and CRP levels. Furthermore, there were statistically significant changes in the P and CRP levels along with the WBC count in the perforated group, but the changes in the Ca levels did not reach significant levels in either the pre- or postoperative periods. With regard to the changes in laboratory values versus those during surgery, the P levels in the perforated group were significantly higher (p=0.045). An increase in P levels alone is not sufficient to make the diagnosis of acute appendicitis. Nevertheless, serum P levels are valuable for the early diagnosis of perforated appendicitis.