The Effects of Dexamethasone Sodium Phosp-hate and Diclofenac Sodium on Wound Healing in Corneal Alkali Burns.

NAZMİ ZENGİN, EMİNE KURT, Özden Vural, Süleyman Okudan, MEHMET OKKA, MEHMET KEMAL GÜNDÜZ

  • NAZMİ ZENGİN: SELÇUK ÜNİVERSİTESİ
  • EMİNE KURT: SELÇUK ÜNİVERSİTESİ
  • Özden Vural: Selçuk Üniversitesi Tıp Fakültesi
  • Süleyman Okudan: Selçuk Üniversitesi Tıp Fakültesi
  • MEHMET OKKA: NECMETTİN ERBAKAN ÜNİVERSİTESİ TIP FAKÜLTESİ
  • MEHMET KEMAL GÜNDÜZ: NECMETTİN ERBAKAN ÜNİVERSİTESİ
  • Year : 1995
  • Vol : 11
  • Issue : 2-3-4
  •  Page : 125-129
Alkali burns of the cornea can result in loss of vi-sual function and anatomical integrity of the eye. In the present study, we evaluated the effect of topical dexamethasone sodium phospate and diclofenac so-dium on wound healing in an akali-burn model using 36 eyes of 18 adult albino rabbits. No dic ference was noted between the effects of two drugs on epithelial healing and fibroblast proliferation, but inflammatory cell infiltration was more pro-minent in the group treated with diclofenac sodium. Our data suggest that dexamethasone sodium phosp-hate is more potent than diclofenac sodium in the treatment of corneal alkali burns.

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Conflict of interest : Yok
This article is published under the CC BY-NC 4.0 license.
Selcuk Medical Journal
1995, Vol. 11 (2-3-4)
ISSN: 1017-6616
E-ISSN: 2149-8059
Received : , Accepted : , Published Online :