The Protective Effects of Verapamil, lopu•inol and Indomethasine on Renal Pa-ranchyme is ESWL Applicated Rabbits

Ercüment Y. Acarer, ALİ ACAR, İBRAHİM ÜNAL SERT, HÜSEYİN VURAL, Esat M. Arslan, Şenol Ergüney, Mehmet Özeroğlu

  • Ercüment Y. Acarer: Selçuk Üniversitesi Tıp Fakültesi
  • ALİ ACAR: NECMETTİN ERBAKAN ÜNİVERSİTESİ
  • İBRAHİM ÜNAL SERT: NECMETTİN ERBAKAN ÜNİVERSİTESİ
  • HÜSEYİN VURAL: SÜLEYMAN DEMİREL
  • Esat M. Arslan: Selçuk Üniversitesi Tıp Fakültesi
  • Şenol Ergüney: Selçuk Üniversitesi Tıp Fakültesi
  • Mehmet Özeroğlu: Çumra Devlet Hastanesi
  • Year : 1994
  • Vol : 10
  • Issue : 3
  •  Page : 361-366
Although it is a safe and effective treatment met-hod in upper urinary tract nehprolithiasis, ESWL has some untoward effects on renal structure and function. It has been reported that verapamil, allopurinol and indomethasine have protective effects on. renal paranchyme, In order to evaluate renal functions in rabbits we studied ESWL related renal paranchymal damage reducing effects of verapamil, allopurinol and in-domethasine. We Used urinary beta NAG. GGT and beta-2 microglobutin levels as relferance. As a result we observed that ESWL. has a focal effects leading to damage on paranchyme which may be temporary ul above mentioned drugs doesn't reduce these effects orswell.

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Conflict of interest : Yok
This article is published under the CC BY-NC 4.0 license.
Selcuk Medical Journal
1994, Vol. 10 (3)
ISSN: 1017-6616
E-ISSN: 2149-8059
Received : , Accepted : , Published Online :