The Renal Cystic Development in Offsprings of Pregnant RaLs That Fed With Diphenylamine Derivates.

ALİ ACAR, ŞÜKRÜ ÇELİK, RECAİ GÜRBÜZ, Özden Vural, Esat M. Arslan, Mehmet Özeroğlu, HASAN HÜSEYİN TELLİ

  • ALİ ACAR: NECMETTİN ERBAKAN ÜNİVERSİTESİ
  • ŞÜKRÜ ÇELİK: AHİ EVREN GÖĞÜS KALP DAMAR CERRAHİSİ
  • RECAİ GÜRBÜZ: SELÇUK ÜNİVERSİTESİ
  • Özden Vural: Selçuk Üniversitesi Tıp Fakültesi
  • Esat M. Arslan: Selçuk Üniversitesi Tıp Fakültesi
  • Mehmet Özeroğlu: Çumra Devlet Hastanesi
  • HASAN HÜSEYİN TELLİ: SELÇUK ÜNİVERSİTESİ
  • Year : 1994
  • Vol : 10
  • Issue : 3
  •  Page : 297-303
The pre vtant rats were fed with diphenylamine derivatives (. tmilorid dihidrat + hid-roelorothiafid) clurin,,? the last week of gestation ins-pired by phanesetin and its major metabolic bre-akdown products are similar chemically diphenvlamine. The di (frrence., that reminded glomerulocystic kidney were -determined with histopathologie exa-mination in kidneys of offvpriti;,- However this dif-frrenees were not noted in olIcpi-inf;s or rats that led normally. We conclude that fetal kidney is susceptible to the interstitial intiantatory elkcts of phanacetin lie-rivairives and the resultmz tubular obstruction pro-duced the cystic changes.

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Conflict of interest : Yok
This article is published under the CC BY-NC 4.0 license.
Selcuk Medical Journal
1994, Vol. 10 (3)
ISSN: 1017-6616
E-ISSN: 2149-8059
Received : , Accepted : , Published Online :