The Use Of Baclofen At Treatment Of Persistent Hiccup In Brainstem Lessions

Hiccup is the sudden onset of erratic diaphragmatic and intercostal muscle contraction and followed by immediate laryngeal closure. Hiccup is usually a self-limited disorder; however when it is prolonged beyond 48 hours, it is considered persistent whereas longer than 2 months are called intractable. The pharmaco therapy of hiccup includes chlorpromazine, gabapentin, baclofen,serotonergic agonists and lidocain. Non-pharmacological approaches are nerve blockade and acupuncture. We report 3 cases presenting with persistent hiccup in brain stem lesions and treated with baclofen.