Treatment of Acetaminophen Poisoning with Cimetidine in Mice

Murat Yurdakök, Melda Çağlar, Kadriye Yurdakök

  • Murat Yurdakök: Hacettepe Üniversitesi Çocuk Sağlığı Enstitüsü
  • Melda Çağlar: Hacettepe Üniversitesi Tıp Fakültesi
  • Kadriye Yurdakök: Hacettepe Üniversitesi Tıp Fakültesi
  • Year : 1987
  • Vol : 3
  • Issue : 1
  •  Page : 51-56
This study was carried out to examine the possible protective effects of cimetidine administration on acetaminophen induced hepatic necrosis in mice. We h.ave observed a drometic protection effect against aceta-'nıinophen hepatotoxicity in cimetidine - treated mice. Cimetidine-treated animals had lower serum transaminases levels and they had less histologicol liver da.mage than those treated with acetaminophen aione.

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Conflict of interest : Yok
This article is published under the CC BY-NC 4.0 license.
Selcuk Medical Journal
1987, Vol. 3 (1)
ISSN: 1017-6616
E-ISSN: 2149-8059
Received : , Accepted : , Published Online :