Clinical and Laboratory Effects of Thyrombolytic Therapy in Acute Myocardial Infarction a Placebo Controlled Study

Talat Tavlı, Bayram Korkut, HASAN GÖK, Alaaddin Avşar

  • Year : 1993
  • Vol : 9
  • Issue : 2
  •  Page : 191-193
Several studies have shown that infarct size is re-duced after trombolytic treatement in patients with acute myocardial infarction. The present study was pelformed to compare clinical and laboratory results in acute myocardial infarction patients following ei-ther intravenous thrombolysis or plasebo in our Co-ronary Care Unite. We peiformed intravenous strep-tokinase (n=46) within 6 hours from onset of chest hain. Total hospitalization days were not changed between patients with thrombolytic treatement and Placebo (10±4 gün vs 11 ±5 gün, p<0.304, respectively). CK-MB started significantly to change after 6 hours (176±138 mgldl, p<0.01). CPK, reached its peak level within 12 hours after thrombolytic treate-ment. SGOT, SGPT and LDII begun significantly change within 18 hours after thrombolytic treate-ment. Cholesterol, trigliserit, LDL were not changed significantly. But HDL increased significantly in pa-tients with thrombolytic treatement within 18 hours after thrombolytic treatment.
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Description : None of the authors, any product mentioned in this article, does not have a material interest in the device or drug. Research, not supported by any external organization. grant full access to the primary data and, if requested by the magazine they agree to allow the examination of data.
Clinical and Laboratory Effects of Thyrombolytic Therapy in Acute Myocardial Infarction a Placebo Controlled Study
, Vol. 9 (2)
Received : 22.10.1993, Accepted : 22.10.1993, Published Online : 22.10.2020
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ISSN:1017-6616;
E-ISSN:2149-8059;