Comparasion Of The Cost-Effectivity For Bacterial Vaginosis
Treatment Protocols
SEVİLAY KILIÇER NAZLI, ALİ HABERAL, ÖZLEM ÖZDEĞİRMENCİ, BURAK KARADAĞ
- Year : 2015
- Vol : 31
- Issue : 2
- Page :
52-56
The possible treatment alternatives for bacterial vaginosis are
500mg oral metronidazole twice a day for one week, vaginal cream
with 2% clindamycin, vaginal gel with 0.75% metronidazole plus
a single dose of 2gr oral metronidazole once a day or 300mg oral
clindamycin twice a day for one week. The purpose of this study is
to compare the treatment effectiveness and costs of oral ornidazole,
local ordinazole with oral ornidazole, vit-C vaginal tablet and 2%
clindamycin vaginal cream. 125 patients who were suitable for the
study were divided in 5 groups randomly with closed letter method.
Groups were formed respectively. Group 1: 500mg oral ornidazole
tablet twice a day for 5 days, Group 2: 500 mg ornidazole vaginal
ovules once a day for 3 days, Group 3: 500 mg ornidazole vaginal
ovules once a day for 3 days plus 500mg oral ornidazole tablet twice
a day for 5 days, Group 4: 250mg vitamin C (Vit-C) tablet once a day
for 6 days, Group 5: one applicator (5gr) of clindamycin vaginal cream
once a day for one week. The patients were recalled 1 week and 4
weeks later after their treatment. The effectiveness of the treatment
were assesed by repeating their inital diagnosis and treatment
methods. Clinical improvement was highest in the combined vaginal
and oral ornidazole group and lowest in the vit-C tablet group. When
we look at the costs of the medicines used in our study, they are
going in an ascending order which is vaginal ornidazole treatment,
vit-C vaginal tablet treatment, clindamycin vaginal cream treatment,
oral ornidazole plus vaginal ornidazole treatment. The differences
between the treatment groups regarding the costs were found
statistically significant (p<0,01). When its relatively low cost and
similar treatment rate of vaginal ornidazole treatment are considered,
it can be chosen for patients who have low socioeconomic level.
Cite this Article As :
Nazlı KS,Haberal A,Özdeğirmenci Ö,Karadağ B.Bakteriyel Vajinosis Tedavi Protokollerinin Etkinleri Ve Maliyetlerinin Karşılaştırılması,Selçuk Med J 2015;31(2): 52-56.
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Description :
None of the authors, any product mentioned in this article,
does not have a material interest in the device or drug. Research,
not supported by any external organization.
grant full access to the primary data and, if requested by the magazine
they agree to allow the examination of data.
Comparasion Of The Cost-Effectivity For Bacterial Vaginosis
Treatment Protocols
2015,
Vol.
31
(2)
Received : 13.03.2013,
Accepted : 13.03.2013,
Published Online : 13.08.2018
Selçuk Tıp Dergisi
ISSN:1017-6616;
E-ISSN:2149-8059;