Correlations Of Vitamin D Level With Hormonal And Biochemical
Parameters In Polycystic Ovary Syndrome
SUNA KABİL KUCUR, İLAY GÖZÜKARA, HAVVA YILMAZ, AYŞENUR AKSOY, EDA ÜLKÜ ULUDAĞ, HÜLYA UZKESER, YASEMİN KAYA, ESRA ADEMOĞLU, AYŞE ÇARLIOĞLU, ŞENAY ARIKAN
- Year : 2014
- Vol : 30
- Issue : 4
- Page :
155-158
To investigate the level of 25(OH)D and association between
25(OH)D level and hormonal-biochemical parameters in Polycystic
ovary syndrome (PCOS). Thirty three patients diagnosed with PCOS
and 42 age- body mass index (BMI) matched control group admitted
to Bolge Training and Research Hospital from May to October were
included in the study. Serum total testosterone (TT), free testosterone
(fT), 25(OH)D, dihydroepiandrostenodione sulphate, LH, FSH, thyroid
stimulating hormone (TSH), cortisol, 17αOH-progesterone, fasting
glucose, insulin levels were evaluated after 12 hour fasting. HOMA-IR
(fasting glucose level x fasting insülin / 405) was calculated. Serum
17αOH progesterone and 25(OH)D levels were significantly lower in
PCOS group (p<0.01). Serum LH, LH/ FSH TT, FT, insulin, ACTH,
and DHEAS levels were significantly higher in PCOS group (p<0.01).
There was statistically significant negative correlation of 25(OH)D
levels with PCOS, LH/FSH, TT, fT, DHEAS ve FGS. There was no
statistically significant correlation between 25(OH)D levels and age,
body mass index and insulin resistance. The results of this study
indicated that vitamin D deficiency is highly prevalent among women
with PCOS independent of body mass index. We also demonstrated
that vitamin D deficiency was correlated with hyperandrogenism in
PCOS women. Low serum 25(OH)D levels might exacerbate PCOS
symptoms. Large intervention trials are needed to evaluate the effect
of vitamin D supplementation on hormonal and clinical parameters in
PCOS women.
Cite this Article As :
Kucur SK,Gözükara İ,Yılmaz H,Aksoy A,Uludağ EÜ,Uzkeser H,Kaya Y,Ademoğlu E,Çarlıoğlu A,Arıkan Ş.Polikistik Over Sendromunda D Vitamini Seviyesinin Hormonal ve Biyokimyasal Parametrelerle İlişkisi.Selcuk Med J 2014;30(4): 155-158
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Description :
None of the authors, any product mentioned in this article,
does not have a material interest in the device or drug. Research,
not supported by any external organization.
grant full access to the primary data and, if requested by the magazine
they agree to allow the examination of data.
Correlations Of Vitamin D Level With Hormonal And Biochemical
Parameters In Polycystic Ovary Syndrome
2014,
Vol.
30
(4)
Received : 23.02.2014,
Accepted : 23.02.2014,
Published Online : 13.08.2018
Selçuk Tıp Dergisi
ISSN:1017-6616;
E-ISSN:2149-8059;