Determining the Effect of Sufentanil on Propofol Injection Pain

Aim: Propofol is a frequently used anesthetic in outpatient anesthesia and pain is often experienced when propofol is injected. Opioids are effective in preventing the propofol pain injection. In this study it’s aimed to evaluate effectivity of sufentanil, a selective μ receptor agonist 5-10 times more effective analgesic than fentanyl, in propofol injection pain. Material and method: Sixty patients scheduled for elective surgery under general anesthesia were randomly allocated to one of two groups to receive either saline 2 ml or 5μg sufentanil before propofol was injected. Each patient was given one of these agents intavenous via 20 G cannula on the dorsum of the hand in 10-20 second. Then 5 ml propofol at room temperature was injected. Pain was assesed verbally and scored none (0), mild (1), moderate (2), severe (3). Results: There was no statistically difference in demographic datas between two groups. In saline group, the incidence of pain (% 80) was higher than in the flidsufentanil group (%46,7) the result was statistically significant (p< 0,05). Conclusion: Pretreatment with 5μg sufentanil was effective in reducing the propofol injection pain. So, we thought that sufentanil can be useful for preventing propofol injection pain.