Distribution Of Candida Species Isolated From Blood Cultures And Invitro Susceptibilities To Amphotericin B And Fluconazole

MUSTAFA ALTAY ATALAY, HAFİZE SAV, GONCA DEMİR, AYŞE NEDRET KOÇ

  • Year : 2012
  • Vol : 28
  • Issue : 3
  •  Page : 149-151
Fungal bloodstream infections are a leading cause of morbidity and mortalite in the immunosuppressed patients. While Candida albicans remains the predominant pathogen, the proportion of invasive candidiasis caused by other species of Candida continues to increase. In this study the identification of the Candida species isolated from blood cultures and investigation of their susceptibilities against amphotericin B and fluconazole was aimed. Candida strains isolated from 97 patients blood cultures within the time period of July 2009-2011 were included in the study. Identification of the strains, germ tube test, morphological appearance of corn meal-Tween 80 agar medium and API 20C AUX (Biomeriux, France) were used. The most common Candida form was C. albicans (68 %) followed by C. parapsilosis (14.5 %) and C. glabrata (9.3 %). Amphotericin B, fluconazole susceptibilities and Minimum Inhibitory Concentrations (MIC) values were measured with E-test method. All Candida strains were susceptible to amphotericin B. Except the flukonazole resistant one and dose-dependent susceptible six C.glabrata isolates, non of Candida isolates were resistant to fluconazole.
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Description : None of the authors, any product mentioned in this article, does not have a material interest in the device or drug. Research, not supported by any external organization. grant full access to the primary data and, if requested by the magazine they agree to allow the examination of data.
Distribution Of Candida Species Isolated From Blood Cultures And Invitro Susceptibilities To Amphotericin B And Fluconazole
, Vol. 28 (3)
Received : 16.02.2012, Accepted : 16.02.2012, Published Online : 13.08.2018
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ISSN:1017-6616;
E-ISSN:2149-8059;