Does Fibromyalgia Syndrome Affect The Treatment And Disease
Activity In Rheumatoid Arthritis?
ÜMİT DÜNDAR, ALPER MURAT ULAŞLI, ÖMER DİKİCİ, TUĞBA ŞENAY, SELMA EROĞLU, HASAN TOKTAŞ, ÖZLEM SOLAK
- Year : 2015
- Vol : 31
- Issue : 2
- Page :
62-64
In patients with rheumatoid arthritis (RA), concomitant
fibromyalgia syndrome (FMS) has been reported in 14-17% of
cases. Several methods are used to evaluate the outcomes in RA.
Among them, disease activity score (DAS 28) is the most frequently
used. The previous studies demonstrated that the presence of FMS
is associated with a significant increase in the DAS 28 scores in
patients with RA. Therefore if, the presence of FMS is ignored if more
aggressive treatment approach can be applied to these patients. The
aim of this study was to assess the frequency of FMS and evaluate
the effect of FMS to disease severity and treatment approach in RA
patients. A total of 74 female RA patients were enrolled to the study
and they were separated in two groups with regards to presence
of concomitant FMS (Group 1 only RA, and group 2 RA with FMS).
The number of tender (TJ) and swollen joints (SJ), erythrocyte
sedimentation rate (ESR) and for pain visual analog scale (VAS)
levels were noted and DAS 28 scores were calculated for RA disease
severity. Additionally, the patients were examined for the presence
of pain in 18 FMS tender points. Group 1 included 44 patients, while
there were 30 patients in group 2. The mean DAS 28 score (3.41 &
4.77, p:0,000), the median number of TJ (4 & 11) (p:0,000) and mean
VAS (21,81 & 45,00) (p:0,000) were significantly higher in group 2.
However, the difference in SJ (0 & 0) and ESR (24.93 ± 18 & 30.33
± 25 mm/h) values were not significant. The type of medication used
for treatment (DMARD or Anti-TNF drug) did not differ according
to FMS existence in RA patients or not whether having FMS or not
in RA patients. This study revealed that, the number of TJ, mean
VAS and mean DAS 28 score are higher in in RA patients having
concomitant FMS in RA patients. RA severity evaluated with DAS28
score may be overestimated due to concomitant FMS which may lead
to inappropriate treatment approaches. There was no difference in
terms of medical treatments because the presence of FMS considered
in our clinic.
Cite this Article As :
Dündar Ü,Ulaşlı MA,Dikici Ö,Şenay T,Eroğlu S,Toktaş H,Solak Ö.Fibromiyalji Sendromu Romatoid Artrit Hastalık Aktivitesini ve Tedavisini Etkiliyor Mu? Selçuk Med J 2015;31(2): 62-64.
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Description :
None of the authors, any product mentioned in this article,
does not have a material interest in the device or drug. Research,
not supported by any external organization.
grant full access to the primary data and, if requested by the magazine
they agree to allow the examination of data.
Does Fibromyalgia Syndrome Affect The Treatment And Disease
Activity In Rheumatoid Arthritis?
2015,
Vol.
31
(2)
Received : 15.04.2014,
Accepted : 15.04.2014,
Published Online : 13.08.2018
Selçuk Tıp Dergisi
ISSN:1017-6616;
E-ISSN:2149-8059;