Effeets of some divalent cations (Mn2+, Cd2+) on the contraction of frog lower oesophageal cir-cular strips indueed by Ca2+ in Ca2+ - free EDTA eontaining mediurn

ERGİN ŞİNGİRİK, Şerare Atçı, Yusuf Karataş, Firuz Baysal, Kansu Büyükafşar, Peyman Uçar, Atilla Dikmen, Serpil Önder

  • Year : 1997
  • Vol : 13
  • Issue : 1
  •  Page : 1-7
Ejjects of Mn2+ and Cd2+ vere investigated on the contracture induced hy I mM CaCl2 in the iso-lated frog lower oesophageal circular segments in-cuhated irt Ca2+ free Ringer solution containing 20 mM KCl and 0.01 mM Na2EDTA, Roth Mn2+ and Cd2+ inhibited the contractures in a can-•entration dependent manner. Cd2+ was found to be more patent than Mn2+ on the Ca2+ induced c:ont-racture. These findings indicated that Cd2+ and Mn2+ can block Ca2+ entry from extracellular space ta intracellulat- compartment.
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Description : None of the authors, any product mentioned in this article, does not have a material interest in the device or drug. Research, not supported by any external organization. grant full access to the primary data and, if requested by the magazine they agree to allow the examination of data.
Effeets of some divalent cations (Mn2+, Cd2+) on the contraction of frog lower oesophageal cir-cular strips indueed by Ca2+ in Ca2+ - free EDTA eontaining mediurn
, Vol. 13 (1)
Received : 13.10.1997, Accepted : 13.10.1997, Published Online : 13.10.2020
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ISSN:1017-6616;
E-ISSN:2149-8059;