Evaluation of the 200 patients' data who had the Diagnosis of Chronic Parachimal Liver Disease from 1989 to 1994 in the Department of Internal Medicine of Selçuk University School of Medicine

This study was performed retrospectively by eı'a-luating the 200 cases. Of cases 130 was male ( 65%, mean ages 50), of them 70 was female (35%, mean ages 55 ). The ratio male/female was 1,8 (p<0,005). In the Ethiologic distribution; HBV(36%) was the striking cause where as HCV (33%) was second and alcohol consumption was the third causal factor. Alt-hough there are some differences in ı-atio, this dist-ribıttion was consistent with the results of other studies in Turkey. On the other hand, while the leading cause of chronic paranchimal liver disease is alcohol con-sumption in Europe and USA, it is HBV, an infectious agent, in developping countries. Weakness and fa-inting, abdominal swelling and loss of appetite and body weight at-e the most prominent svrnptoms. The connnonest abnormality and phvsical exa-mination was hepatomegaly which was followed bı-ascites and splenomegaly. The distribution of symptorns and physical findings were consistent with those in the literature published in Turkeı•. In over study easophagial bleeding to varies was the leading conıplication while hepatic en-cephaloapthy was reported as the comınonest one of chronic liver disease in Istanbul.