Experience Of 114 Patients With Chronic Myeloproliferative Neoplasm

Chronic myeloid neoplasms are pluripotent hematopoetic diseases characterized by maturating and differantiating defects of bone marrow cells and reflecting to peripheral blood. We retrospectively analysed the clinical features of Philedelphia (-) 114 Chronic myeloid neoplasm diagnosed patients of Ege Universty Hematology Department Outpatient Clinic. 58 (49.1%) of patients are female, 56 (50.1%) of patients are male. The median age is 52. 39 of patients has policytemia vera, 23 of patients has primary myelofibrosis, and 52 of patients have essential trombocytosis diagnosis. The appealing sypmtoms are; for 29 of patients have weakness, for 29 of patients have ischemic symptomps, 11 have headache, 8 have pruritis and 3 patients have vertigo. 24 patients were diagnosed incidentally. The mean leucocyte value is 11.163x 〖10 〗^6±5600µL, platelet: 901.336±439.105/µ and hemoglobin:13.8±2.91 g/dl. 25.4% of patients had a story of thrombosis while the 74.6% not. 18 patients are under treatment with anegralide, 26 hydroxyurea, 8 acetylsalisilic acid other patients have combination treatments or under follow up without treatment. This study is one of the largest series in our country.