Glucose Hemeostasis in Children with Cyanotic Congenital Heart Diseases

13 cyanotic congenital heart patients who underwent total correction by open heart surgery method and 5 acyanotic congenital heart patients selected as control for this group were studied. Oral glucose tolerance test, intravenous glucose tolerance test and glucagon tolerance tests were performed in both groups in the preoperative and postoperative periods. A statistically significant difference was found between preoperative fasting blood glucose values ​​and postoperative fasting blood glucose values ​​in the cyanotic group according to the results of oral glucose tolerance test, intravenous glucose tolerance test and glucagon tolerance tests. No such difference was observed in patients with acionetic congenital heart disease. It was concluded that the hypoglycemia observed in these patients may be due to an abnormal glycogulatory hormone secretion or more likely to be caused by a defect in the glycogenolytic or gluconeogenetic enzymatic pathways.