HLA immunogenetic Heterogeneity Turkish Patients with Graves Disease.

HAKKI POLAT, Nurşen Düzgün, AHMET KAYA, Güner Tokgöz

  • Year : 1996
  • Vol : 12
  • Issue : 2
  •  Page : 161-164
Twenty seven Turkish patients with graves di-sease were typed for -B, -C, -DR antigens. There vas a significant increase in HLA-DR3 an-tigens frequency (% 18.51) compared with fifty Tur-kish controls (%4). Our findings support previous reports for im-munogenetk heterogeneity in patients with toxic Graves disease in American whites HLA-DR3 as-sociation was well recognised in most reports (1). HIA associations in Graves 'disease is stronger with HLA-DR loci titan with HLA-B loci (1). We analyzed HLA distibution in our Turkish patients to evaluate the possibility results of previous reports of Turkish Graves 'disease, except for one (13.14.15). In the later, DR4-DR10 association was do-cumented (14).
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Description : None of the authors, any product mentioned in this article, does not have a material interest in the device or drug. Research, not supported by any external organization. grant full access to the primary data and, if requested by the magazine they agree to allow the examination of data.
HLA immunogenetic Heterogeneity Turkish Patients with Graves Disease.
, Vol. 12 (2)
Received : 14.10.1996, Accepted : 14.10.1996, Published Online : 14.10.2020
Selçuk Tıp Dergisi
ISSN:1017-6616;
E-ISSN:2149-8059;