Karyotypic distribution of reciprocal balanced and unbalanced translocations in our laboratory

SEMA TUNCER, ALPER YOSUNKAYA, AYBARS TAVLAN, AHMET TOPAL, SELMİN ÖKESLİ

  • Year : 2002
  • Vol : 18
  • Issue : 2
  •  Page : 123-129
İn this study, karyotipic distribution of reciprocal translocations were investigated in 15 cases who referred to our laboratory because of reproductive vvastage and having a baby with multiple congenital defects. They distributed as follovvs; 6 unbalanced reciprocal translocations; 7 balanced reciprocal translocations and 2 balanced reciprocal translocations with trisomy 21. Ali of the unbalanced karyotypes were partal trisomies and three of them were inherited maternally while the other three were inherited paternally. Family investigations were done in balanced reciprocal translocation carriers and it was seen that three of them were de novo, two paternal and one maternal. Mechanisms of reciprocal translocations, their population rates and risks of carriers were evaluated by using our results.
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Description : None of the authors, any product mentioned in this article, does not have a material interest in the device or drug. Research, not supported by any external organization. grant full access to the primary data and, if requested by the magazine they agree to allow the examination of data.
Karyotypic distribution of reciprocal balanced and unbalanced translocations in our laboratory
, Vol. 18 (2)
Received : 24.04.2001, Accepted : 24.04.2001, Published Online : 02.10.2020
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ISSN:1017-6616;
E-ISSN:2149-8059;