Ocular Findings Of Children With Neurocutaneous Disorders
NİLÜFER İLHAN, ESRA AYHAN TUZCU, ÖZGÜR İLHAN, MUTLU CİHAN DAĞLIOĞLU, MESUT COŞKUN, NESRİN ATÇI, IŞIL DAVARCI, CAHİDE YILMAZ
- Year : 2013
- Vol : 29
- Issue : 4
- Page :
161-164
Ocular findings in children with neurofibromatosis type 1 (NF 1)
and tuberous sclerosis (TS) are presented. The study was conducted
prospectively and comprised 31children who were referred from
pediatric neurology clinic to the ophthalmology clinic. Sixteen of 22
patients with NF1 (72.7%) were male and 6 (27.3%) were female and
the mean age was 9.9 ± 4.2 (3-16 years). Two of 9 patients with TS
(22.2%) were male and 7 (77.8%) were female, the mean age was 5.5
± 3.6 (1.5-12 years). Twenty of children with NF1 had cooperation to
the snellen chart, the mean visual acuity of the right and left eye were
0.93 ± 0.14 (0.4-1.0) and 0.94 ± 0.14 (0.4-1.0), whereas the mean
visual acuity of 7 patients with TS was 0.84 ± 0.22 (0.4-1.0) at the
right and 0.85 ± 0.19 (0.5-1.0) at the left eyes. Percentages of myopia,
hyperopia and astigmatism in children with NF 1 were 40.9%, 4.5% and
18.1%, respectively. Percentages of myopia, hyperopia, astigmatism
in children with TS were 11.1%, 22.2% and 11.1%, respectively. In a
NF 1 patient with keratoconus, his visual acuity was 0.4. Also another
patient with TS had diminished visual acuity of 0.4 at the right eye
and 0.5 at the left eye because of hyperopic astigmatism. Iris Lisch
nodules were detected in 14 (63.6%) of children with NF 1. Five
cases (22.7%) had bilateral optic glioma, the mean age was 7.6 (3-15
years). All tumors were located at intraorbital and the patients were
asymptomatic. Except optic glioma, it was found out that one patient
(4.5%) had bilateral myelinated nerve fibers and the other one (4.5%)
had bilateral optic atrophy due to previous neurosurgery. Sectorial
iris hypopigmentation was determined in one (11.1%) of nine children
with TS. Detailed ophthalmic examination has a great importance
in patients with TS and NF 1 because of ocular findings which are
commonly seen. Patients should be evaluated by ophthalmologists in
terms of refractive error and optic glioma.
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Description :
None of the authors, any product mentioned in this article,
does not have a material interest in the device or drug. Research,
not supported by any external organization.
grant full access to the primary data and, if requested by the magazine
they agree to allow the examination of data.
Ocular Findings Of Children With Neurocutaneous Disorders
2013,
Vol.
29
(4)
Received : 09.02.2013,
Accepted : 09.02.2013,
Published Online : 13.08.2018
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ISSN:1017-6616;
E-ISSN:2149-8059;