Relationship Between Nonalcoholic Fatty Liver and Non High Density Lipoprotein to High Density Lipoprotein Ratio

Aim: The aim of this study was to investigate the relationship between non-alcoholic fatty liver and
demographic characteristics, laboratory parameters and predictory non-high density lipoprotein to high
density lipoprotein ratio.
Material and Methods: Between February and September 2020, 329 patients with fatty liver prediagnosis
were evaluated prospectively. Laboratory (whole blood counts, transaminases, lipid profiles, 25-oh vitamin
d3 levels) and ultrasonography findings, body height, body weight and body mass index of patients were
compared between fatty liver and control groups.
Results: Fatty liver was diagnosed in 164 patients out of 329 participants. There were significant
relationships between existence of fatty liver and age, body weight, body mass index, triglyceride
levels, non-high density lipoprotein, non-high density lipoprotein to high density lipoprotein ratios. Also
relationships between severity of fatty liver and body weight, alanine aminotransferase and body mass
index were found to be significant. There were no relationship between existence of fatty liver and
monocyte to high density lipoprotein ratio and vitamin D levels. Linear regression analysis for Non-HDL/
HDL ratio in diagnosis of nonalcoholic fatty liver, revealed a correlation coefficient as r=0.179. Positive
and negative predictive values for Non-HDL/HDL ratio in diagnosis of nonalcoholic fatty liver were, 56.3%
and 60.9%, respectively .
Conclusion: There is a significant relationship between fatty liver and non-high density lipoprotein to
high density lipoprotein ratio. This ratio may be a simple and readily available predictor in patients with
fatty liver.