SARS-Cov-2 Immunopathogenesis and Possible Anti-Inflammatory Treatment Options

ÖZGE ATAY

  • Year : 2020
  • Vol : 36
  • Issue : 3
  •  Page : 264-273

Towards the end of 2019, new coronavirus causing acute respiratory distress syndrome in patients was detected in Wuhan Province, China . This virus was called serious acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by the International Virus Taxonomy Committee. The disease caused by this new coronavirus was called coronavirus disease-2019 (COVID-19) by the World Health Organization. This virus was found to be in the subclass of Betakoronavirus caused by bats. The role of viral proteins such as envelopes, membranes, nucleocapsids and spike proteins responsible for viral infectivity in immunopathogenesis is being investigated in studies. It has been emphasized in studies in which multiple organ failure develops due to the development of cytokine storm, especially in the advanced stages of the disease. An effective host immune response, including natural and adaptive immunity to SARS-Cov-2, is essential for controlling and treating viral infection. Although there is no effective treatment for the disease today, the benefits of various immunosuppressive and immunomodulatory drugs have been shown in studies. In this article, the immunopathogenesis of SARS-CoV-2 and the treatment models that can be effective on immunopathogenesis are reviewed in the light of current literature.

Cite this Article As : Atay Ö, Asilsoy S. SARS-Cov-2 İmmunopatogenezi ve Olası Anti- inflamatuvar Tedavi Seçenekleri. Selcuk Med J 2020;36(3): 264-273

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Description : None of the authors, any product mentioned in this article, does not have a material interest in the device or drug. Research, not supported by any external organization. grant full access to the primary data and, if requested by the magazine they agree to allow the examination of data.
SARS-Cov-2 Immunopathogenesis and Possible Anti-Inflammatory Treatment Options
, Vol. 36 (3)
Received : 31.08.2020, Accepted : 31.08.2020, Published Online : 02.09.2020
Selçuk Tıp Dergisi
ISSN:1017-6616;
E-ISSN:2149-8059;