The effectiveness of fibrin glue in small bowel anastomoses after mechanical ileus.

Aim: İn this study, the mechanichal resistance of the different kind of anastomoses made traditional suture materials and fibrin glue, and related celi infiltration in small intestine anastomoses performed after mechanical obstuction investigated. Material and Method: This study was performed on 30 rats which were divided into two groups (15 Each) After 24 hours of the mechanical obstructions was made and after 24 hours a traditional suture material anastomoses was performed in one group while fibrin glue anastomose was performed to other group. The bursting pressure of the anastomoses and perianastomose celi infiltration were invastigated in both groups three days later. Results: We observed that, the usage of fibrin glue did not affected the mortality while was found to be more reliable considering leake from the anastomoses . The bursting pressure of the anastomoses made by suture material was 25.7 mmHg which was found to be 23.7 mmHg when fibrin glue was used. Hovvever, there was no statistically significant difference betvveen those two results. Also the celi infiltration was observed to be more when fibrin glue was used compared to other group, but the differce was not statistically significant. İn conclusion, the present study shows that the usage of fibrin glue in accurate concentration and amount might be an effective method in preventing leakage after anastomoses.