The Efficacy Of Concentrated Growth Factor (Cgf) On Temporomandibular Joint Dysfunction

Patients with temporomandibular joint (TMJ) dysfunction have symptoms such as pain in the jaw and surrounding tissues, limitation in jaw movements and/or clicks, crepitation, head, neck, ear, toothache. Although there are publications on PRP injections in the treatment of temporomandibular joint (TMJ) dysfunction, there is no study on the effect of the use of concentrated growth factor (CGF) in the literature. In this study, it was aimed to analyze the efficacy of concentrated growth factor (CGF) in patients with TMJ disc displacement, disc dislocation with/without reduction and joint degeneration. Patients who did not respond to conservative treatment during the period of 2015-2016 and were complaining of TMJ pain, knocking in the joints, decreased mouth opening were included to the study. Magnetic resonance imaging results of before and after injections, age, gender, previous therapies, pain, click on the joint, mouth openness were recorded. The pain felt in the jaw joint in patients was scored according to the visual analogue scale (VAS) numbered 0-10. Mouth openness was measured. Before and the six months after CGF injections, TME magnetic resonance imaging was performed on all patients. All measurements were repeated at 6 months and 1 year after CGF injection. The mean age of the 10 patients (3 males, 7 females) was 30 and the mouth openness was 2.1 cm before injection. In the first year after injection, mouth openness was measured as 3 cm on average. Before injections, there was a clicking sound in all patients. However, at the end of the 1st year, only 2 patients had clicking. The mean VAS before and after injection injection was 8 and 3, respectively. In this study, it was determined that one intraarticular injection of 1 cc CGF in the patients with joint degeneration and TMJ disc displacement with/without reduction resulted in decrease of VAS score and click sound and increase of mouth openness. CGF injection may achieve symptomatic improvement in patients with TMJ dysfunction.