THE EVALUATION OF THE EFFECTS OF IONIC AND NON-IONIC CONTRAST MATERIALS ON THE MORPHOLOGY OF HUMAN ETHROSIDES IN VITRO BY PHASE-CONTRAST MICROSCOPE

In this study, Ionic contrast media (UrografinR % 76 - Diatrizoate, Shering A. G) ifp fifteen cases and non-ionic contrast media (Ultravist` Iobromid, Shering A. G) in fifteen cases were used for intravenous pyelo-graphic examinations. It was examined as invitro the ef-fects of these contrast medias on the huınan eritrocytes morphology. Red cells reserve their morphologic structure in isotonic saline. It was reported that they loose their biconcave disc form in different ratios of ionic and non-ionic contrast medium solutions. In 90 percent volume ratio (contrast medium/blood) of the ionic contrast medium, morphologic changes of the red cells induced significantly higher percentage. Uhen the same ratio of the non-ionic contrast medium is used, the less morphologic changes occured in 5, 10, 20, 25 percent volume ratio (contrast medium/blood) of the non-ionic contrast medium. Induced changes in the red cells morphology were low level. It was reported that the induced changes on the red depend on the contrast media osmolality application as invitro.