The Production and lise of Mortoclonal Antibody
A. Zeki Şengil, BÜLENT BAYSAL
- Year : 1989
- Vol : 5
- Issue : 3
- Page :
166-172
The technic for the producrion of immortal clones of cells making single antibody specificities by fating normal antibody-forming B lymphoblasts with an appropriate myeloma cells are achived by Kale,. and Milstein in 1975. These cells so celled "hibridornas" are selcted out iım a tissue cıdıure medimın. Monoclonal antibody and hibridoına technology are used in the speration of individual cell types with specific surfaces markers, diagnosis of lyrnphoid and myeloid ?nalignancies, tissue typing. And also yfr,ill be used in tufnour therapy (magic bullet) with cytotocric agents coupled to antiturnour-specific antibodies.
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None of the authors, any product mentioned in this article,
does not have a material interest in the device or drug. Research,
not supported by any external organization.
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The Production and lise of Mortoclonal Antibody
1989,
Vol.
5
(3)
Received : 20.11.1989,
Accepted : 20.11.1989,
Published Online : 20.11.2020
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ISSN:1017-6616;
E-ISSN:2149-8059;