The Role Of Mean Platelet Volume In Predicting
Diabetic Complications
ATİLLA BIYIK, CEVDET DURAN, ŞAMİL ECİRLİ, ORKİDE KUTLU
- Year : 2015
- Vol : 31
- Issue : 3
- Page :
105-108
The mean platelet volume (MPV); is a marker that gives
information about platelet function, activity, and volume. Increased
MPV indicates larger platelets which are more active and inclined
to more adhesion and aggregation. In diabetics, increased adhesion
and aggregation can lead to blockage in the microvascular system,
diabetic complication, ischemia, and hypoxia. We compared MPV
in patients with microalbuminuria (MA) and/or patients with/without
hypertension (HT) who have type 2 diabetes mellitus (DM) as an
indicator of complications. Eighty patients (aged 18-65) with/ without
MA and/or HT with type 2 DM and 30 healthy subjects were included
into the study and divided into 4 groups as Group 1: Type 2 DM without
HT and MA, Group 2: Type 2 DM with HT and without MA, Group 3:
Type 2 DM without HT and with MA, Group 4: Type 2 DM with HT and
MA. The MPV’s of patients in Group 2, Group 3 and Group 4 were
higher than controls (p=0.005,p<0.001, p<0.001, respectively), but
not higher than Group 1. The mean MPV values in diabetic patients
were significantly higher than the controls (p<0.001). Although higher
MPV levels were found in diabetic patients compared to control, MPV
levels are not useful in monitoring and predicting complications in
type 2 DM patients.
Cite this Article As :
Bıyık A,Duran C,Ecirli Ş,Kutlu O.Ortalama Trombosit Hacminin Diyabet Komplikasyonlarını Öngörmede Rolü,Selçuk Med J 2015;31(3): 105-108.
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Description :
None of the authors, any product mentioned in this article,
does not have a material interest in the device or drug. Research,
not supported by any external organization.
grant full access to the primary data and, if requested by the magazine
they agree to allow the examination of data.
The Role Of Mean Platelet Volume In Predicting
Diabetic Complications
2015,
Vol.
31
(3)
Received : 31.12.2014,
Accepted : 31.12.2014,
Published Online : 13.08.2018
Selçuk Tıp Dergisi
ISSN:1017-6616;
E-ISSN:2149-8059;