The Use Of Antifungal Drugs Used In Newborn

SELVİ GÜLAŞI, ÜMİT ÇELİK

  • Year : 2018
  • Vol : 34
  • Issue : 1
  •  Page : 40-50
Invasive candidiasis is responsible for about 10% of nosocomial sepsis and it continues to be significant cause of serious morbidity and mortality in very low birth weight infants. Alhough the informations about the antifungal drugs which used for Candida species are increasing, studies and conclusions about the efficacy and safety are still insufficient. Most of the studies have focused on the pharmacokinetic and pharmacodynamic evaluations and obtained from adult patients. However, efectiveness of the therapy can not be same in newborns due to the different pathophysiology of neonatal candidiasis in newborn, the inferences can not be considered from adult studies. Until now, amphotericin B deoxycholate, fluconazole and micafungin seems to be effectivev therapy for the treatment of neonatal invasive candidiasis. Herein, the medical literature has been scanned and compiled with the latest information about the use of antifungal agents in newborn.
Cite this Article As : Gülaşı S, Çelik Ü. Yenidoğanlarda Antifungal İlaç Kullanımı. Selcuk Med J 2018;34(1): 40-50

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Description : None of the authors, any product mentioned in this article, does not have a material interest in the device or drug. Research, not supported by any external organization. grant full access to the primary data and, if requested by the magazine they agree to allow the examination of data.
The Use Of Antifungal Drugs Used In Newborn
, Vol. 34 (1)
Received : 01.01.2016, Accepted : 01.01.2016, Published Online : 13.08.2018
Selçuk Tıp Dergisi
ISSN:1017-6616;
E-ISSN:2149-8059;