Management Of A Term Pregnant Women Who Has Diagnosed With Factor 7 Deficiency Which Previous Pregnancy Was Resulting At Vaginal Childbirth

Congenital factor VII (FVII) deficiency is an uncommon bleeding disorder with an estimated incidence of 1/300.000-1/500.000. Congenital Factor VII deficiency is an otosomal recessively inherited and 0.5% of all congenital coagulation disorders. Factor 7 deficiency is the fourth of all congenital factor deficiencies in the Factor 8, Factor 9, and lack of the Von Willebrand Factor. It affects men and women in the same proportions. Although there is no correlation between FVII level and bleeding risk. An important part of the patients are asymptomatic until advanced age, often by chance, is investigating the bleeding parameters, only PT’s long, APTT is normal due to the received diagnosis. Fresh frozen plasma (FFP), FVII, prothrombin complex concentrates (PCC), plasma-derived factor VII (pdFVII); recombinant activated factor VII (rFVIIa) are used for prophylaxis or treatment of bleeding. In this case, a pregnant woman at term which her first pregnancy was resulting in vaginal childbirth without any problem, but factor 7 deficiency was detected in her second pregnancy and there was also no problem to term is presented to cesarean operation with recombinant activated factor FVII for the preparation and post-operative management.