Protective Effects of Verapamil, Allopurinol and Endomethasin in the Histopathological De-triages Occured During ESWL Procedures in Rab-bits.

Ercüment Y. Acarer, ALİ ACAR, İBRAHİM ÜNAL SERT, Özden Vural, Mehmet Özeroğlu, MURAT BÜYÜKDOĞAN, ŞÜKRÜ ÇELİK

  • Ercüment Y. Acarer: Selçuk Üniversitesi Tıp Fakültesi
  • ALİ ACAR: NECMETTİN ERBAKAN ÜNİVERSİTESİ
  • İBRAHİM ÜNAL SERT: NECMETTİN ERBAKAN ÜNİVERSİTESİ
  • Özden Vural: Selçuk Üniversitesi Tıp Fakültesi
  • Mehmet Özeroğlu: Çumra Devlet Hastanesi
  • MURAT BÜYÜKDOĞAN: SELÇUK ÜNİVERSİTESİ
  • ŞÜKRÜ ÇELİK: AHİ EVREN GÖĞÜS KALP DAMAR CERRAHİSİ
  • Year : 1994
  • Vol : 10
  • Issue : 3
  •  Page : 401-408
ESit'L is a safe and commonly used therapeutic modallyty in the treatment of upper urinary system stones. However, clinical studies have revealed some structural deformities in kidneys following ESWL treatment. The renal paranchymal protective effects of some drugs, such as verapamil, allopurinol and in-domerhasin are well known. In this study, the renal parandvmal demages due to ESWL and the protective effects of verapamil, al-lopurinol and indomethasin on this dernage were ey-perimentaly investigated in rabbits. Macro and microscopic changes in the effected kidney, after ESWL applications, were demostrated but no protective results of those drugs were ob-served even though the drugs had increased harp jill effects in the kidneys.

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Conflict of interest : Yok
This article is published under the CC BY-NC 4.0 license.
Selcuk Medical Journal
1994, Vol. 10 (3)
ISSN: 1017-6616
E-ISSN: 2149-8059
Received : , Accepted : , Published Online :