The Glimins In The Treatment Of Type 2 Diabetes

The prevalence of type 2 diabetes is increasing world wide and it is estimated to rise from 382 million today to 582 million by 2035. Although there are a number of therapies currently avaible to treat diabetes mellitus, glycemic control rates remain poor. Imeglimin, the first in a new-tetrahydrotriazine-containing class of oral antidiabetic agents and it has been shown to decrease hepatic glucose production, increase glucose uptake in skeletal tissue and improve insulin secretion in response to glucose. In this text, the efficacy and safety of imeglimin in the treatment of type 2 diabetes are reviewed.