Selçuk Tıp Dergisi Arşiv

The pre vtant rats were fed with diphenylamine derivatives (. tmilorid dihidrat + hid-roelorothiafid) clurin,,? the last week of gestation ins-pired by phanesetin and its major metabolic bre-akdown products are similar chemically diphenvlamine. The di (frrence., that reminded glomerulocystic kidney were -determined with histopathologie exa-mination in kidneys of offvpriti;,- However this dif-frrenees were not noted in olIcpi-inf;s or rats that led normally. We conclude that fetal kidney is susceptible to the interstitial intiantatory elkcts of phanacetin lie-rivairives and the resultmz tubular obstruction pro-duced the cystic changes.

Complications of Diabetes mellitus are beleived to be resulted from altercations in insulin ho-meostasis and energy metabolism. Metabolic stress, by increasing oxidative stress causes jimctional and structural damage which results in diabetic comp-lications. The formation of free radicals as a result of an increase in oxidative tetil.ity increases in Un-controlled diabetes mellitus. In organisms, an-tioxidant defense systems are present agains harm-ful effects Of free radicals. In the present study. sermon vitamin E and ervt-hrocyte superoxide disimuase (SOD) and ght-tathione peroxidase (GSH-P.►-) activities of 33 he-alty subjects aged between 34-b6 and 57 patients with type II diabetes mellitus under treatment and aged between 35-75 nears have been investigated. Erythrocyte SOD and GSII-Px activities and serum Otani'', E level of patients were 550±200 U g 11b. 26.7±12.8 g lib and 472.6±183 ftg ill whereas these of controls were 649±165 .. gr 21.8±6.2 U gr III and 422.7±145 fig;d1 res-pectively. The difference between the parameters of the two groups were nor significiant statistically. - Since no significiant alteration was found in the activity of antioxidants. it was concluded that tre-atment of diabetes mellitus might prevent preduction of, free radicals.

Fine needle aspiration biopsy %vas pet:formed in 6 patients with diagnosed retroperitoneal masses by routine •adiologic investigation in our clinic in the last I year. In 4 patients renal cell carcinoma, in 1 patient hematoma, in .1 patient perirenal abscess was di-agnosed with fine needle aspiration biopsies. Renal cell carcinomas MU corrected with histopathologic examination of nephrectomy specimen. The patient ►•ith hematoma was treated conservatively. We conclude that fine needle aspiration biopsy to be a simple, cheap and relatively noninvasive for preoperative tissue diagnosis.

in last decade the radial artery pediele .forearm fast-lc-wan .flap is more uselful than the other con-ventional methods. Because of its popularity, pri-ority and advantages in circulatory physiology and anatomy it is used on repairing of defects in hands. In our clinics, in 9 patients. between 11-60 years old, the defects occured in both side of hands (dor-sal and paten art have been repaired by distal pe-die/es radial fasciocutan island flaps (1,14)1- an int-mobilLation period of 10 dais post-op hands motion and rehabilitation have been started and both ,for-mal and fonctional access have been achieved.

Suture patterns of 100 skulls front the archives of anatong departments of medical schools of Selruk, flacettepe and Aegean Univers* ---ilswer-e in-vestigated. Also antero-posterior cranial ra-diography of 30 elementary school children were obtained to determine the cranial suture patterns at youngers ages. LainbdOid and COR-a sutures were compared -with each other in terms of sutural pattern forms and the area of 3-untre patterns. The morphologic he-terogeneity of cranial sutures were also studied. In this study age dependent sutural pattern can not be assertaineed. The obliteration of sutures occur with ageing. Metopic sutures containing skulls also had l'OrMian bones corallary to other studies published else villere.

Pelvic fractures associated with blunt trauma contributed significantly to morbidity and mortality.We reviewed 271 patients with pelvic fractures which were treated between March 1985 and Sep-tember 1994 in this study. Tint average age of pa-tients was 26.7 (between 3-70) years. The majority of the patients (%41.3) had one or more associated injuries: 43 with blunt abdominal trauma, 27 with - genitourinary tract injuries, 23 with thoracic in-juries, 22 with head trauma, 4 with neurologic in-juries and 3 with vascular injuries. There were Jive open pelvic fractures. Altough the overall mortality was %5.5 the mortality rate in. unstable pelvic "'Fac-tures was %9.6. The major causes of death in our patients were closed head injury, intra-abdontinal and intro-pelvic hemorrhage. The pelvic .fractures with associated injuries are serious trauma and re-quire more prompt and effective treatment methods.

From 1984 to 1994. 11 patients with urererocele suffering from liank pain, dysuria, pollacuria were admitted to our hospital of these patient 5 had right ureterocele, 3 left ureterocele and 3 also bilateral ureteroceles_ .Transurethral incision for 5 cases were applied, transurethral partial resection for 3 cases, both t•ansvesical resection and ureteroneocystostomv for 3 cases. Treatment and results in the patients with ureterocele have been discussed.

For 15 patients with superficial bladder tumor suffering from hematuria, dvsuria, pollacuria, ur-gency have been reffered our clinic applied tran-surethral resection between March 1993-June 1994. Second transurethral resection was performed approximated)! 1 month after the initial Iran-surethral resection in cell patients b) same urologist. In 7 patients of 15 patients residual tomtit- was con-firmed hitologically at resection area after second TUR. It was understood that second transurethral re-section performed determined interval in patients H.,ith superficial bladder tumors succesfid alternative-for prevent and confirm of residual tumor.

In. the repairing of tibial defects which were oc-curred by different causes, using of ipsilateral vas-tidal-Led graft of fibula which has the pellicle ofpe-roneal arter, improves rapid healing and reduces the risk of infection, avascular necrosis and hos-pitalisation. On suitable cases, we have preferred and advised this method performed on six cases in our clinic.

Although it is a safe and effective treatment met-hod in upper urinary tract nehprolithiasis, ESWL has some untoward effects on renal structure and function. It has been reported that verapamil, allopurinol and indomethasine have protective effects on. renal paranchyme, In order to evaluate renal functions in rabbits we studied ESWL related renal paranchymal damage reducing effects of verapamil, allopurinol and in-domethasine. We Used urinary beta NAG. GGT and beta-2 microglobutin levels as relferance. As a result we observed that ESWL. has a focal effects leading to damage on paranchyme which may be temporary ul above mentioned drugs doesn't reduce these effects orswell.

41 patients with retroperitoneal mass were ope-rated in the Selcuk University medical Faculty Uro-logy' Clinic between 1984-1994. For 15 patients midline approach, for 11 patients paramedical app-roach, for 10 patients ntodllied thoracoabdominal approach, for 4 patients subcostal flank approach were applied_ Surgical tipproaches. early ambulation, mor-bidity, days of hospitilization, early and late comp-lications due to incision were evaluated. More succesfill results are obtained with 1110- dified ihOraCOabdOillinal approach titan other app-roaches for retroperitoneal amasses.

This is a descriptive and corss sectional type of study which was performed among the activities of "World AIDS Day" on 1 st November in 1994 in the two schools of apperentic-eship in KONYA The aim of the study was to determine the difference of know-ledge levels of the students before and aft e4: edu-cation about AIDS. In the study group the total number of the stu-dents were 414 and 11 of them were girls. The stu-dents mean age 1.'as 16.2, 38 (92 %) of the students were graduated from primary school, 33 (8 %) of them were graduated from secondary school. 3 of the students were married, one of them was widowed and the others were unmarried. Their income was 70.000 weekly. The knowledge level of.the 474 students about AIDS was determined by using a questionnaire form about this subject. An education progranune was per- brined by the instructors of microbiology de-partment after the using of questionnaire form. 10 days after the education programme the same qu-estionnaire forms were used again. The results were determined by t. test. A special composite index was developed to determine the know-lad,ge levels. The composite index was 37. The knowledge points before education was bet-ween 0 and 27, the mean was 11.0 After education there was an increase of 18.1 % point. TVlien eva-luated hi t test this increase was si,,f;inficant at the 0.01 level. AIDS is an illiess which-can be prevented by edu-cation. Education of one hour by instructions had been supplied an increase o f.18r in the knowledge level. We think that it will be usefull of AIDS is reached among the education programmes.

The case histories and urodynamic findings of 34 women who presented with stress incontinence ad-mitted to Selcuk University Medical FallikV Uro-logy Clinic were evaluated. In all patients nra flow-merry, filling. cystometry, urethral pressure profilometry, stress urethral pressure profilometry WeIC performed Also in 11 beaky women same eva-luations 1.vere lrerifurrrled. 34 patients with (*Molly stress incontinence of 24 patients jvere diagnosed genuine stress incontinence as a result of urodynamic evaluation. We suggest that in patients With 51,1111710111S stress incontinence the urodynamic evaluation of bladder and ureihml func-tions that performed after obtaining a detailed history is valuable in choice of treatment.

It was reported that cila:april, a new ACE in-hibitor, decreases arteial blood pressure, ine-reases regional flows by 25 %. in the kidney, 37 gf in the stomach, 57(. in the ileum and 37 % in the skin in spontaneously hyper tansive rats. 11-e evaluated the effects of treatment with ci-la:april (2.5 mg once a day) to kidneys in rats with renovasetilar hvertension that occurred partial renal artery SIC110SiS.

0/ 24 patients Irvith a DSIU-111-R diagnosis of manic episode, aged 16-6/in giffki physical health. 12 ii-ere randomly allocated to receive car-bama:epine and 12 lithium to appraise the an-cliiracy and side effects were evaluated with repect tra _y-1lainhta Behavior Assesment Seale, Brief Psychiatric Patin!,.! Scale (BPRS). pa-tients reports and clinici,w obwrration. At the end (../ the Slifdy. :;i0h11 ciinicai improvement 11. vs- seen In 91 mcr of patients and in 58.3q Of respect to Bun-Bchavifir -1,s-Nerne111 Scale alit' BPRS lithium showed also significantly superiority to car-banta:epine (p<0.033). The ino,s( Ircquent side cf-feels in ca•baina=epine Qom].) heileici•he (50(.: (2.5%), nausea i25‘:, ) Ifoileici, in the la-tllitlrt2roup any side (.16-0 was not ,oserved at a rah: of 25C

Many different methods have been used for the identification Helicobacter pylori in upper gast-rointestinal system. The activity iirease in Chris-tensen cigar, CLO test and microscopical oh-s'eryation in histopatolog_ycal cross sections .were comparied. in this study the aim is to research He-licobacter pylori existence in antral biopsy spe-cimens from 57 patients with peptic ulcer.

ESit'L is a safe and commonly used therapeutic modallyty in the treatment of upper urinary system stones. However, clinical studies have revealed some structural deformities in kidneys following ESWL treatment. The renal paranchymal protective effects of some drugs, such as verapamil, allopurinol and in-domerhasin are well known. In this study, the renal parandvmal demages due to ESWL and the protective effects of verapamil, al-lopurinol and indomethasin on this dernage were ey-perimentaly investigated in rabbits. Macro and microscopic changes in the effected kidney, after ESWL applications, were demostrated but no protective results of those drugs were ob-served even though the drugs had increased harp jill effects in the kidneys.

Subtalar dislocations are uncommon in juries. The case report. of a 20-years-old male who sus-tained a medial subtalar dislocation, is presented. In this discussion. the etiology and treatment of medial subtalar dislocation is reviewed to alert the cli-nicians for prompt evelnation

In. this article, a case with interventricular sep-tum rupture which is one of the most serious coup-lications of acute myocardial infarction was int-roduced. The clinical situation of the patient with acute inferior myocard inlarction f1 /5 evaluated with the Doppler echocardiograph. Owing to this case differential diagnosis. diagnostics methods. prognosis and the best treatment of intervetricular septum rupture with acute myocardial infarction was discussed.

A rare complete lateral .fracture-dislocation of the lumbar spine without paraplegia is reported. A 23 year-old man injured by traffic accident. Fixation offracture-dislocation ti aS obtained using Abet Spi-nal System without trying reduction. Long-term fol-low up (3 years after operation) showed an excellent result.

Midolazam is a short acting benzodiazepine type drug that has recently entered clinical use.

Psoriasis is chronic and inflainatory diseases which characterised with epidermal cell pro-liferation. There is a common. opinion about etiology of psoriasis which is explained with faulty im-munological respons of cells. It is emphasised that impaired T cell function is responsible of pathogenesis of the diseases. It has known. that cyclosporin-A is im-munsupresif and has selective efficacy on ke-ratinocysts and chronic intlamatory cells. By this re-ason in recent years it has begun to use cyclosporin-A, more frequently to cure psoriatic patients.