IZOLE KOBAY MIDE FUNDUSUNDA KARBAKOL'E BAGLI KASILMA UZERINE PINAVERIUM BROMID, VERAPAMIL YE DILTIAZEM'IN INHIBITOR ETKILERI

Ekrem Çiçek, ESRA KISMET ATALIK, H. İbrahim Karabacak

  • Year : 1995
  • Vol : 11
  • Issue : 2-3-4
  •  Page : 167-170
izole kohay mide fundusunda ycipilan hu in vitro calimada, pinaverium ve kalsiyum an-tagonistlerinden veraparnil ile diltiazemin karhakole bagli kasilmalar iizerine plan gev4.etici etkileri Haztrlanan mide fundus stripleri icinde Krebs-Henseleit soliisyonu hulunan izole organ hanyosuna alimp. 104 M karhakol ile kasildt. Elde edilen hu kasilmalar iizerine kiimiilatif konsantrasyonda (10-9 -104M) uygulanan antagonistlerin doza hagrmlr bir ekilde gevxmeye neden oldugu goriildii. Elde edilen bulgular, izole kohay mide fun-dusunda kullamlan antagonistlerin, karhakole bagli kasilma cevaplarini anlarnlr olarak inhibe ettigini ye 1050 degerlerine gore gii• siraiamasinin pi-naveriun7=verapamil>diltiazem Rklinde oldugunu gastermektedir (p<0.05).
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Description : None of the authors, any product mentioned in this article, does not have a material interest in the device or drug. Research, not supported by any external organization. grant full access to the primary data and, if requested by the magazine they agree to allow the examination of data.
IZOLE KOBAY MIDE FUNDUSUNDA KARBAKOL'E BAGLI KASILMA UZERINE PINAVERIUM BROMID, VERAPAMIL YE DILTIAZEM'IN INHIBITOR ETKILERI
, Vol. 11 (2-3-4)
Received : 15.10.1995, Accepted : 15.10.1995, Published Online : 15.10.2020
Selcuk Medical Journal
ISSN:1017-6616;
E-ISSN:2149-8059;