Makale Arama

It has been reported different results about the prevalence of Helicobacter pylori infection in patients with psoriasis. In several studies, although the prevalence of Helicobacter pylori was reported to be increased, in some studies it could not be shown same results. In this study, we aimed to evaluate the prevalence of Helicobacter pylori infection and the association between disease activity and infection in patients with psoriasis. A total of 11 (8 male, 3 female) patients with psoriasis and 23 healthy controls (18 male, 5 female) were included in the study. Helicobacter pylori infection was diagnosed with biopsy which was obtained from the antrum and the body of stomach or with urea breath test. Before and after Helicobacter pylori eradication, disease activity was revealed with psoriasis area severity index. Sequential eradication regimen was preferred treatment for helicobacter pylori. Urea breath test was used to evaluate the eradication after the treatment Nine (% 82) of 11 patients with psoriasis had positivity for Helicobacter pylori while 11 subjects (% 47,8) of 23 had positivity for Helicobacter pylori in the control group. After the eradication treatment, Helicobacter pylori were negative in six patients. Four patients returned for follow-up visits and psoriasis area severity index had significantly resolved in only one of them. In conclusion, however the number of patients is so not much, in this study the prevalence of Helicobacter pylori was observed to be more frequent in patients with psoriasis but no association between disease activity and infection was found. Further studies are needed to show the association between disease activity and Helicobacter pylori infection.

The place of surgical treatment, except for the treatment of complications, in peptic ulcer gradually decreases. Helicobacter pylori eradication with proton pump inhibitors (PPI) and H2 receptors that have been used frequently recently have played important role in this decrease. One of the most common complications of peptic ulcer, though protective medicines, is still perforations and they are very common among surgical emergencies. The files of 311 patients with peptic ulcer perforation accepted to the clinic between 2000-2010 were examined retrospectively. The patients applied to our clinic with peptic ulcer perforation were examined in terms of age, sex, seasonal relation, and applied surgical technique. 206 of the patients were male with 52.8 mean age and 105 of them were female with 65.2 mean age. 266 of the patients were fixed with primary suture, 35 of them had bilateral truncal vagotomy+pyloroplasty and 10 were fixed laparoscopically. Average hospitalization time was 7 days. While wound infection developed in 25 of the patients, evisceration was developed in 8 patients, 9 patients were exetus. Over the last ten years there has been a change from definitive attempts to primary fixation and from laparotomy to laparoscopic methods for treatment of peptic ulcer perforations our clinic.

Propolis is a resin collected by honeybees from various plant sources, has attracted the attention of researchers due to its several biological and pharmacological properties in recent years. The aim of this study was to investigate the antimicrobial activity of ethanolic extract of propolis (EEP) collected in Kayseri and its surroundings against some clinically important microorganisms. In the study, Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Klebsiella pneumoniae, Helicobacter pylori, Candida albicans, Candida glabrata strains were used and agar dilution method was performed to investigate of antimicrobial activity according to the CLSI. By using microbroth kinetic system based on continuous monitoring of changes in the optical density of bacte¬rial growth, turbidimetric growth curves of a model bacteria (S.aureus) in the presence of increasing concentrations of EEP were also generated and determined minimum inhibitory concentration (MIC). MIC values of EEP against tested microorganisms were found between 64 and 1024 µg/ml by agar dilution method. The results in microbroth kinetic system were similar to the agar dilution method for S.aureus and in vitro antimicrobial susceptibility was determined in an earlier stage. Kayseri propolis have shown antimicrobial activity against common pathogens, is important to evaluate the availability of treatment.

İn this study, the prevalence of H.pylori-lgG antibody was investigated in 83 hemodialysis (HD) and 30 CAPD patients and compared with those of 45 healthy control group. İn determination of IgG antibody against H.pylori enzyme immunoassay ELİSA method was used. Mean ages were 46.2+17.4 and 44.6+15.7 years and dialysis durations were 35.4+ 36.9 months and 20.2+18 months in HD and CAPD patients respectively. Age of control group was 49.4+15.3 (18-80) years. H. Pylori-antibody was positive in 36 HD patients (43.4 %), in 9 CAPD patients (30 %) and in 19 healthy Controls (42.2 %). Hp-lgG antibody positivity in HD and CAPD patients was not statistically different from control subjects. İn conclusion, there is no assosiation between Hp-lgG antibody posi­ tivity and age, sex, dyspeptic symptoms two groups. İn this patients Hp IgG positivity should not be evaluated with- out endoscopic and.histopathologic findings.