13 articles published in Selcuk Medical Journal with the keyword "sıçan": Investigation of Morphine-Induced Dopamine Release in the Nucleus Accumbens by Fiber Photometry; The Effects of Topiramate on Methotrexate- Induced Pancreatic Injury; Does Experimental Morphine Addiction in Rats Change Physiological and Histological Characteristics of the Heart?
YASIN ALI ÇIMEN, SELIM KUTLU
2025, Vol 41, Issue 4, Page 194-200
Objective: Morphine is an opiate frequently used in the management of acute and chronic pain. Sequential use of morphine increases dopamine levels in the nucleus accumbens (NAc) through activation of dopaminergic neurons in the ventral tegmental area. The aim of the study was to investigate...
FILIZ MERCANTEPE, LEVENT TÜMKAYA
2023, Vol 39, Issue 2, Page 94-91
Aim: The present study aimed to investigate the effects of topiramate on pancreatic islets of Langerhans cells in Methotrexate-related pancreatic injury. Materials and Methods: The study was conducted between 04 July - 24 July 2022 in the Animal Research Unit of Recep Tayyip Erdogan University....
HANDE ÇAĞLIYAN, Z IŞIK SOLAK GÖRMÜŞ, HATİCE SOLAK, RAVİYE ÖZEN KOCA, BURCU GÜLTEKİN
2022, Vol 38, Issue 3, Page 128-135
Aim: Morphine is one of the most preferred opioids in treatment of chronic pain. Recurrent use can cause addiction. There is no consensus on cardiovascular system treatment/side effects of opioids. In order to investigate effects of opioid addiction on heart, myocardial contractility/histological...
AYDAN CANBİLEN, REFIK SOYLU
1992, Vol 8, Issue 2, Page 193-198
In this light microscopic study, morphology of nasal mast cells was investigated in rats using alcian blue- safranin 0 and toluidin blue staining methods. The investigation was performed on 10 mak and female albino rats which were obtained from the Ex-perimental Animal Laboratory of the Faculty of...
AYDAN CANBİLEN, SABİHA SERPİL KALKAN, HASAN YÜCE
1992, Vol 8, Issue 3, Page 353-357
In this ligin microscopic study, the ellects of morphine sulfate on nasal mast celis was in-vestigated using alcian blue-safranin O and to-luidin blue staining methods. The investigation was peıformed on 20 m❑le and female albino rats which were obtained from the E.xperimental Animal Laboratory of...
AYDAN CANBİLEN, AHMET SALBACAK, SELÇUK DUMAN
1993, Vol 9, Issue 2, Page 226-231
In this light microscopic study, the effects of cromolyn sodium on nasal mast cells of rat was itıvesiigated using alcian blue-safranin O and toluidin blue staining methods. The investigation was peıformed on 20 male and female albino rats which were obtained from the Experimental Animal Laboratory...
OSMAN ÖZCAN, SELÇUK DUMAN, KEMAL IRMAK, HÜSEYİN UYSAL, HASAN KOÇ
1993, Vol 9, Issue 2, Page 197-204
in this study whose object was to invest the ef-fects of nitrogen mustard in the level of LD5o and LDloo on nonmalignant tissues 30 rats were used. The effects of nitrogen mustard which was giyen int-raperitoneally to pregnant rats were investigated with light microscope. In the liver degenerative...
AYSEL KÜKNER, JALE ÖNER
2001, Vol 17, Issue 3, Page 165-169
İn this study, experimental hypothyroidism in rats was induced using 6-propyl-2-tiouracyl (PTU) and its effects on kidney, glomerule and tubules structure were investigated at microscopic level. İn the experiments, 60 days old 12 female rats which weighted 200-250 gr were used. The rats were...
İLTER KUŞ, HAKAN ÖNER, AHMET SONGUR, MUSTAFA SARSILMAZ
2002, Vol 18, Issue 1, Page 9-17
This study was aimed to examine the effects of ovariectomy and ovariectomy follovved by estrogen administration on the pineal gland by light microscopy. For this purpose 15 female Wistar rats vvere used. Animals were divided into three groups. Group I and II vvere designated as sham-ovariectomised...
LEYLA CANBOLAT KOYUTÜRK, NERIMAN ÇOLAKOĞLU
2002, Vol 18, Issue 2, Page 83-88
The renin angiotensin system is thought to be modulated by gonadal steroids. After unilateral nephrectomy and unilateral nephrectomy + bilateral ovariectomy, occured changes were investigated in this study. Right nephrec- tomized and rigth nephrectomized + bilateral ovariectomized female rats left...
ALPARSLAN GÖKÇIMEN, ÖZDEN ÇANDIR, MEHMET ALİ MALAS
2002, Vol 18, Issue 4, Page 213-221
İn our study, kVe have aimed to search the findings seen on the tissue specimens taken from the liver, kidney, ovary, testis and pancreas of many rats that have been poisoned by long- term high doses of florid. Twenty rats which belong to VVistar Albino species were being eçually separated into two...
İLTER KUŞ, JALE ÖNER, AHMET SONGUR, OĞUZ ASLAN ÖZEN, MUSTAFA SARSILMAZ
2003, Vol 19, Issue 1, Page 1-8
This study was undertaken to examine effects of pinealectomy and pinealectomy followed by melatonin adminis- tration on thyroid gland. For this purpose 18 male VVistar rats were used. Animals were divided into three groups. Group I and II were designated as sham-pinealectomized (control) and...
İSMAIL ZARARSIZ, M. FATIH SÖNMEZ, H. RAMAZAN YILMAZ, HIDIR PEKMEZ, İLTER KUŞ, MUSTAFA SARSILMAZ
2004, Vol 20, Issue 3, Page 93-98
In this study the toxic effects of formaldehyde to lungs and protective effects of omega-3 fatty acids against these toxic effects were investigated at histological and biochemical levels. For this purpose, 21 adult male Wistar rats were divided into three groups. Rats in group I were used as...
rat degranulasyon degranulation Nitrogen mustard böbrek kidney ovariectomy melatonin Bağımlılık dopamin fiber fotometri GRAB sensörleri morfin nalokson Addiction dopamine fiber photometry GRAB sensors morphine naloxone