Makale Arama

Seroprevalance of hepatitis C and HIV are viral diseases transmitted by blood transfusion and sexual contact. In this study we aimed to evaluate the seroprevalance of hepatitis B, hepatitis C and HIV at healthy volunteer blood donor who applied to the blood center of Meram Medical Faculty of Selcuk University. HBsAg, anti-HCV and anti-HIV test results were evaluated retrospectively between January 1993-June 2003 at 169708 blood donor who applied our blood center. HBsAg prevalance in the healthy blood donor which applied our center was 7.3% in 1993 and decreased by years to 1.6% in 2000, 1.7% in 2001, 2.1% in 2002, 1.8% in first half part of 2003. Anti-HCV prevalance in these donors were 0.24% in 1997, 0.25% in 1998 and 1999, 0.23% in 2000, 0.10% in 2001, 0.20% in 2002 and 0.15% in first half part of 2003. Anti-HIV test was reactive in 8 sera but by the confirmation test no positive test was found. The average HBsAG prevalance was 3.8%. The improvement was provided in Hepatitis B, C and HIV prevalance in blood donors by the way of vaccination and education. As a result the HBsAg prevalance was decreased gradually. Anti-HCV prevalance was decreased in 2001 according to 1998-99. However the prevalance of hepatitis C was not decreased because vaccination was not possible.No HIV positive blood donor was found during six years. This is due to HIV doubtful blood donors separated by means of blood donor information form or these kind of person don’t want to be a blood donor.

All employees (N=498) of Seydişehir Public Hospital’s (SDH) were included, who were working in the period of 2013 and 2015, in the study in order to assess their seroprevalence of Hepatitis B virus (HBV), Hepatitis C virus (HCV) and Human Immunodeficiency Virus (HIV). After getting the official permission, data on employees’ personnel follow-up forms (health information forms) kept by the Hospital’s Infection Control Unit and records of Hospital Information Management System (HIMS) were retrospectively analyzed. Results showed that employees were HBsAg (+), anti-HBs (+) and anti-HCV (+) as in 0.8%, 86.7% and 0.2% levels, respectively. A statistically significant relationship between occupational status (doctor, nurse/ medical staff, health technician, cleaning personnel and other group) and anti-HBs was found (p<0.001). In the further analysis, the proportion of anti-HBs (+) was lower in the other group (including medical secretary, biologist, psychologist, dietician, pharmacist, security, kitchen worker, driver, information processing, technical service, tailor, social worker, and researcher) than the groups of doctor, nurse / health officer, health technician, cleaning staff. There was no difference in terms of anti-HBs between doctor, nurse / health officer, health technician and cleaning staff group (p=0.442). Also, a statistically significant relationship was observed between the employed units (internal services, surgical services, operating room, intensive care unit, emergency services, dialysis, laboratory and other units). An important difference for anti-HBs seropositivity was found (p=0.011). In the further analysis, the ratio of anti-HBs positivity was lower in the other units including kitchen, security, data entry and technical service than internal services, surgical services, operating room, intensive care, emergency service, dialysis and laboratory groups. There was no difference in terms of anti-HBs positivity among the internal services, surgical services, operating room, intensive care, emergency service, dialysis, and laboratory groups (p=0.717). There were no statistically significant relations of the HBsAg seropositivity with the employed unit (p=0.96) and the professional status of the employees (p=0.566). Consequently, HBV, HCV and HIV seroprevalence levels of SDH employees were in parallel with the other studies.

To determine the seropositivity ratios of hepatitis-B and hepatitis-C in pregnant women living in Kocaeli region. Three thousand seven hundred and fifty-six pregnant women who applied to Izmit Women and Child Health Hospital for delivery (vaginal delivery, cesarean) were included in this retrospective study. HBsAg, AntiHBs, Anti-HCV and Anti-HIV were detected by macro ELISA system in all pregnant women. Data were analysed with the SPSS statistical programme. Seropositivity of HBs-Ag, Anti-HBs and Anti-HCV were detected 2.2%, 3.7% and 0.3% respectively in pregnant. There were no pregnant women who have seropositivity with Anti-HIV. The results detected for seropositivity of hepatitis-B and hepatitis-C in Kocaeli region are similar to those found in other regions of Turkey.

İn this study the seropositivity of antiHA VlgM and IgG, HBsAg, HBeAg, antiHBe, antiHBs, antiHBdgM, antiHBc and antiHCV were investigated in the sera of 96 staff working at the kitchen of different goverment departments and 100 healthy people. İn the sera of staff vvorking in the kitchen antiHAVIgG was 93.7% (90/96) positive and in the control group 92% positive. AntiHAVIgM was found negative in ali of the staff and control group. The seropositivity of HBsAg, HBeAg, antiHBe, antiHBc and antiHBs were found as 5.2, 2.1, 3.1, 17.7, 14.6 % respectively in the control group these markers were found 7, 7, 0, 27, 34 % respedively. AntiHBdgM was negative in al! of the sera. Anti HCV was found positive at one kitchen staff and at the two person of the control group. For the staff who were negative for hepatitis A and B virüs markers a vaccination programme was planned.

The purpose of this study was to designate the prevalences of Toxoplasma, Rubella, Cytomegalovirus, HBV, anti-HBs, HCV, HIV among first trimester pregnant women and investigate the relationship between age groups, parity. This study included 2900, under 12 gestational weeks pregnant women, ages ranging from 16 to 45 admitted to Bayrampasa State Hospital obstetrics and gynecology outpatient department between November 2011 and February 2013. Toxoplasmosis, rubella, cytomegalovirus, HBV, hepatitis B infection, HCV, HIV was studied in suitable pregnant women and results were analyzed. Age groups, gravida, parity number were questioned. The mean age of the pregnant women participating in the study was 27.78±5.57 (16-45), mean gestation was 2.21±1.39 (1-8), mean parity was 0.78±0.89 (0-5), mean gestational age on admission was 8±3 (5-12). Toxoplasma IgG, Rubella IgG, Cytomegalovirus IgG, HBsAg, antiHBs, HCV, antiHİV seropositivity were respectively 31.2%, 95.7%, 99.2%, 2.4%, 22.1%, 0.1%, 0%; and Toxoplasma IgM, Rubella IgM, cytomegalovirus IgM seropositivity percentages, were respectively 0.9%, 0.15%, 0.7%. Toxoplasma seropositivity rate is similar to Turkey data. Rubella seronegativity was found lower then the data of Turkey and with the prepregnancy vaccination this value can be pulled the level of European countries. The high level of CMV seropositivity in our study indicates the low socioeconomic status. HBsAg, anti-HBs, anti-HCV and anti-HIV levels were close to the average of Turkey. According to them, in addition to routine screening of TORCH, screening for HBsAg and anti-HBs appears appropriate, anti-HCV and anti-HIV screening is not cost effective.

During the period of 18 months between 1 Ja-nuary 1994 and 30 June 1995, 166 cases were hos-pitalized as viral hepatitis in Selguk University Me-dical Faculty, Department of Infectious Diseases. 86 of the cases (51.8 %) were male There were 41 pa-tients (24.7 %) in and below 18 years old, 83 pa-tients (50%) between 19-39 years old, 26 patients (15.7 %) between 40-59 years old and 16 patients (9.6 %) in and above 60 years old. Number of the whole cases in 1994 were 105 and 53 of them (50.5 %) were male. Total number of cases in 1994 were 61 and 36 of them (59 %) were female. Of the cases, 122 (73.5 %) were from city-center of Konya, 35 (21.1 %) were. from vicinity of Konya and 9 (5.4 %) were from out of Konya. When one evaluate the cases as monthly in 1994, it can he seen that june was to had the lowest number of the cases (4 cases),and on the other hand, in 1995, January was to had the highest number of the cases (22 cases). Types of the cases were tested with HBsAg, Anti HBc 1gM, HBeAg, Anti-HBe, Anti-HBs, Anti-HAV 1gM, Anti-HDV, Anti-HCV. According to the results of these tests, the types couldn't been determined in 66 (39.8 %) of the cases. Among the remaining cases, 67 cases (40.4 %) were Hepatitis B. 11 cases (6.6 %) were Hepatitis A, 8 cases were (4.9 %) Chronic active hepatitis, I case (0.6 %) was Delta hepatitis, 3 cases (1.8 %) were Fulminant hepatit, I case (0.6 %) was Lupoid Hepatit and 5 cases (3 %) were considered as Liver paranchym disease. Mean hospitalization time was 13.5 days in 1994 and 16.7 days in 1995. The longest mean hos-pitalization time in 1994 was belonged to Hepatitis B as 16.5 days and in 1995 it was also belonged to Hepatitis B as 18.6 days. The cost of the illness per a person in 1995 was 250$.

The infections caused by human immun deficiency virus (HIV), Hepatitis B and C virus pose a serious occupational risk for the healthcare workers especially those in emergency service, laboratory and surgery wards. Vaccination and establishment of the strict biosafety procedures are the main principles to prevent bloodborne infections in healthcare workers. Additionally, serological screening of the preoperative patients could decrease the risk for exposure. In this study, we aimed to determine the seroprevalence of HBsAg, AntiHCV, Anti-HIV ½ in preoperative urological surgery patients. A total of 260 patients (184 (%70.8) male, 76 (% 29.2) female were included in the study. HBsAg, anti-HCV and anti-HIV ½ seropositivity of the patients admitted to Urology Clinic for elective surgical procedures between March 2008-December 2010, were evaluated retrospectively. Among all patients included in the study, a total of eight patients- six male, two female- were HBsAg positive and one male patient were positive for Anti-HCV. Anti-HIV ½ positivity was not detected. The seroprevalence of HBsAg and Anti-HCV were; 3.1% (n=8) and 0.4% (n=1), respectively in patient group. Although statistically significant relationship was not detected, HBsAg positivity rate was higher in male patients than female patient group. HBsAg and Anti-HCV seropositivity rates in our study group showed concordance with the low rates reported previously in our country. Besides educational programmes to healthcare workers about bloodborne diseases, vaccination against hepatitis B, implementation of strict biosafety precautions during surgery process considering any patients as potential carriers, preoperative serological screening of the patients should be useful to reduce the risk of occupational exposure.

Tumors In This study, anti-HCV seropozitivity was inves-tigated in 46 new diagnosed patients with different solid tumors without hepatocelluler carcinoma, which they have not received any transfusion or sur-gical operation. The positivity was evaluated using by second generation ELISA system. Patients are consist of 14 lung cancer (Ca), 7 lymphoma, 5 breast Ca, 5 hipernephroma and 15 other tumors. Anti-HCV positivity was in 5 (10.8%) of 46 pa-tients, and 4 of this positive patients were with lung Ca (4114,28.5%), and 1 was with brain Ca (113). ALT levels were normal, serum iron and iron-binding capacily were decrased in all patients, hae-moglobin and haemotocrit were also decreased in 73.9% of patients. In addition, 3 patients (6.5%) HBsAg, 21 patients (45.6%) anti HBc were found to be positive. As a result, the high positivity of anti-HBc while the HBsAg was low positive showed that there was IIBV infection, and the HCV infecton was alsa expected with the same transmission ways. Anti-HCV positivity as a marker of HCV infection-which can produce the chronic carrier state is more expected in cancer patients. They have allected immun status than normal population, but 4 of 5 posi-tivity was in Lung Ca patients is of great interest.