Koagulaz - Negatıf Stafılokoklar Uzerıne Topıkal Antımıkrobıyal Ajanların Etkisi
Effect Of TopIcal AntImIcrobIal Agents On Co-Agulase-NegatIve StaphylococcI
Deri yazeyinde hulunan koagalaz-negatif sta-filokoklara topikal olarak uygulanan antimikrobiyal ajanlarin etkirzligi araorrildr. 5 antiseptik solusyon ye 5 antimikrobiyal pomat degerlendirildi. Antiseptik solusyonlar (% 10 Po-. vidone-iodine, % 2 iodine, % 2 Tentardiyot, % 70 etanol, % 0.5 Klorhekzidin) gazli hezle 15 saniye uy-gulandi. Antimikrobiyal pon-zadlar (mupirocin, neomycin-bacitracin • silver sulfadiazirz, povidone-iodine pomad. sodywn fusidat) gazli hezle 6 saw sareyle tathik edildi. Tedavi uygulamalarrndan sonra arnekler Povidone-iodine. Klorhekzidin ye tentiirdiyot dim Orneklerde (10110) yilzey bakterikrini eradike etti. % 2 iodine 10 ornegin 9'unda, % 70 etanol ise lo ornegin 7'sinde eradike edici hulundu. 5 antimikrobiyal pomadm 471 deri yazeyinin ste-rilizasyonunda etkin hulundu. % Silver sal-fadiazinVe 10 ornekten 2'cinde koagiilaz negatif sta-filokok arernesi goralda.
In the Human Skin The efficacy of antimicrobial agents applied to-pically to the skin surface in eradicating coagulase-negative staphylococci (ENS) residing in the skin surface. Five antiseptic solutions (10 % povidone iodine, 2 % iodine, 2 % tincture of iodine, 70 % ethanol, and 0.5 % Chlorhexidine) were applied for 15s with a gauze sponge. The antimicrobial ointments (po-vidone-iodine. silver sulfadiazine, mupirocin, so-dium fucidate, and a double-antibiotic ointment con-taining neomycine, and bacitracin) were applied and covered for 6 th with gauze. After treatment. the surface was sampled. All agents were effective in eradicating ENS from the surface. The antiseptic solutions povidone-iodine. chlor-hexidine and tincture of iodine eradicated surface bacteria in every trial (10 of 10 each), and 2 % io-dine and 70 % ethanol eradicated bacteria from the surface in 9 and 7 of 10 trials, respectively. Four of the five antimicrobial ointments were also effective in the sterilization of the skin sur-face: 1 % silver sulfadiazine was the exception.