Makale Arama

İn our study 85 (40 male and 45 female) human skulls were obtained from skeletal collections belong to the Anatomy Department of the Medical Faculty, University of Selçuk. İn this study the use of anthropometric data from the skulls to evaluate the gender differences, and to identify their anthropological cranial types according to the cephalic indices results. Anthropometric skull measurements were used to establish a comparative study betvveen the obtained literatüre data from previous anthropometric studies on skulls from Aşıklıhöyük area belong to Neolithic age (5000-3000 B.C.) and skulls from Panaztepe area belong to Islamic period (800 A. D.) on one hand, and on the other hand, skulls belong to contemporary individuals from Konya city (Mid-Anatolia) and Ceyhan city (Sourthern Anatolia),who died during the tvventieth century. The results demonstrated that bi-orbital and bizygomatic measurements showed significantly higher values in males (p<0.05) those can be used in the gender differentiation. İn males, cephalic index was 79.07 ± 5.22, in females it was 79.50 ± 5.76. İn males %30.7 of the skulls and in females %41.6 of the skulls were demostrated the Mesocephal (oval-shape) type which was found to be the most common type in the present study.

İn this retropective study, patients with atherosclerotic risk factors and the related clinical diagnosis, angiographic scoring and regional distribution were investigated. A total of 630 patients (450 male, 180 female, mean age 56,2 ± 9.3) t hat underwent coronary angiography were enrolled. Patients were classified according to the clinical characteristic and Reardon’s modified severity scoring which is the indicator of the extend of coronary artery disease, was calculated. A parallel increase in coronary disease along with higher triglicehdes was observed, which was significantly different betvveen single and double vessel disease(p<0,05). The same correlation was apparent between HDL levels and the extent of the disease vvhich was remarkable in single and triple vessel disease group (p<0,05). Triglyceride levels varied as higher in males younger than 60 year of age vvhile smoking was lower in the same group (p<0,05). On the other hand hypertension was observed more frequently in elder patients (<60 year of age) (p<0,05). As a conclusion, ali risk factors other than smoking appeared to be higher than TEKHARF cohort, which were given for Central Anatolia region.

Background: Electromagnetlc fields (EME) are the most important environment problems that effect the public health in our century. Increasing incidence of coronary heart disease, leukemia, lymphoma, and Alzheimer in the patients who are effected from magnetic fields, are revealing that these sources can not be used unlimitedly. İn this study, we would like to investigate the effect of hairdryer on the rats. Materials and methods: İn this study, 200-250 gr weighted 29 male rats vvere used. 15 of them were control group, and 14 vvere faced with EMF. A BKK 1161 SK hairdryer was used as the magnetic field source. This machine had 600 VVatt (W) power, 220 V - 50 Hz resistance, and a mean magnetic field counted 100-150 mG. The distance betvveen the subjects and the machine was 20-25 cm. EMF was performed on them for 3 days of each week, and 5 minutes of each day, and it was lasted after 3 months with a total period of 205 minutes. At the end the malondialdehid (MDA) levels in the subjects sera vvere calculated, and they vvere sacrificed and their cerebrum, thymus, lungs, heart and great vessels, liver, kidneys, and spleen vvere taken to histopathologic examination under light microscope. Results: İt was obviously observed that the EMF in 50 Hz freguency increases the mononuclear celi infiltration in the viscera; especially, it was estimated that EMF causes alveolar destruction in the lungs, tubuler degeneration in the kidneys, glial proliferation in the cerebrum, fibrosis in the liver, and adventitial mononuclear celi infiltration in the great vessels in 3 months, vvhich is thought to be a very short period. Statistically, the subendothelial dissection in the great vessels was not found significant, hovvever, this was thought to be an important finding. The serum MDA levels of EMF group vvas increased, but statistically, this was not significant. Conclusion: We concluded that EMF causes an increase in the production of free oxygene radicals, and in the late-term this results with various diseases including cancers and atherosclerotic dişe ases.

Serum selenium levels were investigated in both 65 cases who are living where white muscle disease of lambs were often observed and 33 cases where the disease seen rarely. The selenium level was 60.425±11.727 in first group and 70.849±12.868 pıgli, in the second and statistically significant difference was observed between the two groups (p<0.01). Particulary in the first group the selenium level was lower (han the values which reported as normal (78-320 !mit) selenium levels. Epidemiological and clinical studies indicate that low selenium levels can be an etiological cause for cardiovascular disease. Therefor it may be suggested that determination of coronary risk factors, incidance of coronary heart disease and fulfilling of prospective studies relatid with the subject would be usefil.

Objective: Familial hypercholesterolemia (FH) is an autosomal dominant inherited genetic disorder that causes a significant increase in low-density lipoprotein (LDL) cholesterol levels and leads to early coronary heart disease and cardiac mortality. Although this disease has a heterozygous (HeFH) and homozygous (HoFH) form, the incidence of HeFH is reported to be 1: 500, while HoFH is reported to be 1: 1 000 000. This disease is often caused by LDL receptor (most common), apolipoprotein B (Apo B), Proprotein Convertase Subtilisin/Kexin 9 (PCSK9), and LDL receptor adaptor protein (LDLRAP) gene mutations. Patients with FH do not respond well to lipid-lowering therapies such as a statin, and so lipoprotein apheresis is the treatment of choice.

Material and Methods: We compared the results of lipoprotein apheresis in a 20-year-old female patient diagnosed with HoFH with two different methods [double-filtration plasmapheresis (DFPP) and dextran sulfate column (DSC) methods]. 40 lipoprotein apheresis procedures including 20 sessions of DFPP and 20 sessions of DSC were evaluated.

Results: When the two methods were compared the changes in high-density lipoprotein, white blood cells, platelets, potassium, calcium, prothrombin time (INR) and activated partial thromboplastin time values were statistically significant.

Conclusions: In conclusion, our study suggests that it would be more appropriate to choose the apheresis method according to the clinical and laboratory findings of the patient since it shows that two different methods have different effects on serum electrolyte values, hemostasis criteria and leukocyte and platelet counts.

We investigated hypertension incidence among °at patients and the patients from the province in Konya. The first group included 1000 randomized out patients and the. second group included 2036 patients examined during health sereening studies in certain areas. We used World Health Organisation criterias for hypertension diagnosis. In first group hypertension incidence among patients under 45 years old was 22.5%, 46-60 years 44.5%, 61 years and over 60.3% and the mean 32.5%. In second group hypertension incidence among patients under 45 years oid was 14,2%, 46-60 years 42.2%, 61 years and over 44% and the mean 23,1%. The hypertension incidence increases gradually in older patients and most of them are mild cases, obesite and diabetes mellitus are important risk factors, cerebrovascular accident, cardiac and renal pathologies are the most common complications.

The aim of this study is to report our surgical results in ventricular septal defects. Between 2001 and 2009, 92 patients with ventricular septal defect underwent surgical correction in our center were included in this study. Additional cardiac defects were pulmonary hypertension in 27 (29.3 %) patients, patent ductus arteriozus in 10 (10.8 %) patients, Down Syndrom in 7 (7.6 %) patients, and aortic regurtation 5 (5.4 %) patients. Defects were closed with Dacron patch using separately sutures. Early mortality was developed in 5 (5.4 %) patients. 65 patients were followed for 6.1 years. Residual VSD was detected in 3 patients and one of them underwent secondary operation. There was no complet atrioventriculary block. 1˚- 2˚ degree aortic and tricuspit regurtation were not operated and included in our follow up programme. We hope to perform surgery for ventricular septal defect with low mortality and morbidity as a new Middle Anatolian center.

Major malformation screening was made in 7868 mewborns at Konya Maternity and Children Care State Hospital, Turkey, January through October in 1988. Newborns, 28 weeks old and over were subjected to physical examination and the blood type determinations when needed. Blood type determinations were made for all mothers who gave birth. During 10 months period, of the 7868 babies born 3762 were female and the remaining 4106 babies were males. Among the 218 stillborn babies, 95 of them were female and 123 were males. 75 babies born with major malformations, and 66 (88%) of 75 had single and the remaining 9 (12%) had multiple malformations. The overall incidence is found ta be 0.9% and 0.11% for single and multiple malformations, respectively. About 51% of 66 newborns had musculo-skeletal system, 30% central nervous system, 14% digestive system, 1,5% circulatory systern, 1,5% urogenital system malformations, respectively. Also, musculo-skletal system malformations were found more often in males than female infants. Similarly, pes equino-varus was predorninant among the males whereas polydactylism among the females. In musculo-skeletal malformation system, stillbirth frequency is rather low (3 females and 1 male out of 33 malformed cases). The most stillbirths were seen in central nervous system (13 female and 3 male out of 20 cases). Anencephalus seemed to appear more often in female infants !han the male ones, and anencephalus and hydrocephalus females were stillborn infants. Multiple major malformations

The current study aimed to determine the in our country patients diagnosed peripheral arterial disease (PAD), the relationship with the atherosclerotic risk factors. A better understanding of the risk factors will make it possible to take precautions against the modifiable risk factors, and will facilitate the early diagnosis and implementation of effective therapy. The patients who had been diagnosed with PAD either clinically or by using ultrasonography underwent peripheral angiography for the arteries of the lower extremities. The patients were evaluated in terms of age, gender, and atherosclerotic risk factors. Of the 408 patients, 78.4% were males, and the mean age was 61.5±9.5 years. The patients had the following risk factors: hypertension (HT), 58.3%; diabetes mellitus (DM), 26.7%; a family history of CAD (Coronary artery disease), 15.9%; smokers, 48.2%; hypercholesterolemia, 49.7%. The extent of PAD observed during peripheral lower extremity angiography was associated with atherosclerotic risk factors. Particular attention should be focused on the co-morbidities of PAD. Non-invasive, as well as invasive tests, should be performed when indicated to decrease morbidity and mortality in patients at risk for PAD.

It is a know that morbidity of cardiovascular disorders is high in diabetic patients. Besides obesity and hypertension, increased levels of triglycerides and very low density lipoprotein cholesterol were identıfied among high risk factors in the development of coronary arter disease in patients with abnormal oral glucose tolerance test. In this study, i1 is compared with risk factors and coronary heart disease among the patients with 60 abnormal glucose tolerance test and 60 type-II diabetes mellitus and 60 normal cases. Body muss index is found high in patients with' aıabetes melliıbıç and abnormal glucose tolerance les( It was higı- levels of systolic and diastolic blood pressuı e in patients with diabetes mellitus and abnormal glucose rolerance test. The level of triglycerids and totaı s holesterol and fasting blood sugaı were high in patıenıs with diabetes mellitus and abnormal glucose tolerance test, but it was low level of high density liport.teın cholesterol in both groups. It is identıfied mort ınactivelife standart regarding life style in both Finally these results suggested that the risk tactors of coronary artery disease increased in patients with abnormal glucose tolerance test lıke diabetes mellitus

Wild honey intoxications are usually seen in Marmara and Black Sea regions in Turkey. In this report. ye present the patient with wild honey in-toxication. who showed ischemic ST segment dep-ression during tachycardia that occured after tre-memoir with turopin of severe sinusal bradycardia. We performed coronary angiogt-why because of ha-ving ST segment depression during tachycardia epi-sode and found coronary artery disease in the co-ronary angiography of the same patient.

High-density lipoproteins (HDL) have preventive effects from developing atherosclerosis (11, 13, 24). In order to investigate the effects of long-term drugs nifedipine and propranolol on HDL cholesterol concentrations in the treatment of CHD and hypertension, 20 patients who were given nifedipine, 20 patients who were given propranolol and 20 healthy controls were studied. Serum HDL cholesterol concentrations were lower in patients with coronary heart disease (CHD) than in the control group (P <0.05). There was a significant decrease in HDL cholesterol levels in the propranolol group (P <0.01), but no change in those given nifedipine. Total cholesterol values ​​did not differ significantly, and there was no change with drug intake. Total / HDL cholesterol ratio increased in those given propranolol, but did not change in those given nifedipia. We concluded that administration of propranolol for long-term treatment of KH and hypertension reduces IIDL cholesterol levels, but administration to nifedipine did not.

Sustainability is satisfying the needs of present generation by pro tecting presence and quality of resources that future generations will need. A sustainable nutrition system refers to a diet with low environmental impacts which contribute to food and nutrition security for healthy life for present and future generations. Nutrition systems has changed as a result of growing global population, developing the technology, urbanization and industrialization. This situation result in environmental problems as water resources and land uses and increasing greenhouse gases emissions in addition to several health problems notably increasing cronic diseases incidence. Environmental changes and nutrition systems are interrelated. A nutrition model which is containing animal based food enough and plant based can supply sustainability of health and environment.

Aim: This study aimed to evaluate vitamin D levels, which were determined over a year in the pediatric
clinic of a training and research hospital in Central Anatolia, according to age groups, gender, and
seasonal characteristics.
Patients and Methods: This retrospective study was conducted using the data of children aged 0–18
years who applied to the children’s clinic of a hospital between January 2019 and December 2019 and
whose vitamin D levels were determined. Children were divided into five different age groups, 28 days–12
months, 13 months–2 years, 2–5 years, 6–11 years, and 12–18 years, in accordance with Standard 6
recommendations. Vitamin D levels were evaluated in terms of age group, gender, and admission season.
Results: A total of 9496 children, 5360 (56.4%) females and 4136 (43.6%) males, were included in the
study. A 25(OH)D level below 20 ng/mL (representing a deficiency) was found in 6472 (68.2%) of the
participants, while 2085 (21.9%) participants had a 25(OH)D level between 21–29 ng/mL (representing an
insufficiency) and 939 (9.9%) participants had a 25(OH)D level over 30 ng/mL (representing sufficiency).
It was determined that vitamin D levels are lower in girls than in boys, vitamin D levels are inversely
proportional to age, and vitamin D levels reach their lowest values in winter and highest values in summer.
The effects of age group, gender, and season of admission on vitamin D levels were statistically significant
(P < 0.001).
Conclusion: The mean vitamin D levels for all age groups were either insufficient or deficient. Vitamin D
levels in children aged 0–18 is related to age, gender, and season. Necessary measures should be taken,
especially for at-risk groups, to prevent vitamin D deficiency or insuf ficiency.

This study was peıformed on 71 coronary heart patients (51 male, 20 female, 44-78 years old) and 55 healthy subjects (25 male, 30 female, 42-73 years old). In the patients with coronary heart disease, int-raerythrocytic cholinesterase (EACHE) levels, plas-ma cholinesterase I HDL (CRF) and int-raerythrocytic cholinesterase I HDL ratios (VRF) were higher and plasma cholinesterase activities were lower than values of control group. It was concluded that in addition to ERF and CRF, EACHE I IIDL ratio (VRF) might be an im-portant risk factor for coronary heart disease.